日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PlyKp104, a Novel Phage Lysin for the Treatment of Klebsiella pneumoniae, Pseudomonas aeruginosa, and Other Gram-Negative ESKAPE Pathogens

PlyKp104,一种用于治疗肺炎克雷伯菌、铜绿假单胞菌和其他革兰氏阴性ESKAPE病原体的新型噬菌体裂解酶

Euler, Chad W; Raz, Assaf; Hernandez, Anaise; Serrano, Anna; Xu, Siyue; Andersson, Martin; Zou, Geng; Zhang, Yue; Fischetti, Vincent A; Li, Jinquan

Regulatory control of the Streptococcus mutans HdrRM LytTR Regulatory System functions via a membrane sequestration mechanism

变形链球菌HdrRM LytTR调控系统的功能是通过膜隔离机制实现的。

Xie, Zhoujie; Zou, Zhengzhong; Raz, Assaf; Qin, Hua; Fischetti, Vincent; Zhang, Shan; Kreth, Jens; Merritt, Justin

The Antistaphylococcal Lysin, CF-301, Activates Key Host Factors in Human Blood To Potentiate Methicillin-Resistant Staphylococcus aureus Bacteriolysis

抗葡萄球菌溶素CF-301可激活人血液中的关键宿主因子,从而增强耐甲氧西林金黄色葡萄球菌的溶菌作用。

Indiani, Chiara; Sauve, Karen; Raz, Assaf; Abdelhady, Wessam; Xiong, Yan Q; Cassino, Cara; Bayer, Arnold S; Schuch, Raymond

Isolation of Phage Lysins That Effectively Kill Pseudomonas aeruginosa in Mouse Models of Lung and Skin Infection

分离出能有效杀灭小鼠肺部和皮肤感染模型中铜绿假单胞菌的噬菌体裂解酶

Raz, Assaf; Serrano, Anna; Hernandez, Anaise; Euler, Chad W; Fischetti, Vincent A

Is IL-1β Further Evidence for the Role of Propionibacterium acnes in Degenerative Disc Disease? Lessons From the Study of the Inflammatory Skin Condition Acne Vulgaris

IL-1β是否进一步证实了痤疮丙酸杆菌在椎间盘退行性疾病中的作用?从寻常痤疮这种炎症性皮肤病的研究中汲取的教训

Slaby, Ondrej; McDowell, Andrew; Brüggemann, Holger; Raz, Assaf; Demir-Deviren, Sibel; Freemont, Tony; Lambert, Peter; Capoor, Manu N

Lysostaphin Lysibody Leads to Effective Opsonization and Killing of Methicillin-Resistant Staphylococcus aureus in a Murine Model

溶菌酶溶菌体在小鼠模型中可有效调理并杀灭耐甲氧西林金黄色葡萄球菌

Raz, Assaf; Serrano, Anna; Thaker, Maneesha; Alston, Tricia; Fischetti, Vincent A

Lysibodies are IgG Fc fusions with lysin binding domains targeting Staphylococcus aureus wall carbohydrates for effective phagocytosis.

溶菌抗体是 IgG Fc 与溶菌素结合域的融合蛋白,靶向金黄色葡萄球菌细胞壁碳水化合物,以达到有效的吞噬作用

Raz Assaf, Serrano Anna, Lawson Christine, Thaker Maneesha, Alston Tricia, Bournazos Stylianos, Ravetch Jeffrey V, Fischetti Vincent A

Propionibacterium acnes biofilm is present in intervertebral discs of patients undergoing microdiscectomy.

接受微创椎间盘切除术的患者的椎间盘中存在痤疮丙酸杆菌生物膜

Capoor Manu N, Ruzicka Filip, Schmitz Jonathan E, James Garth A, Machackova Tana, Jancalek Radim, Smrcka Martin, Lipina Radim, Ahmed Fahad S, Alamin Todd F, Anand Neel, Baird John C, Bhatia Nitin, Demir-Deviren Sibel, Eastlack Robert K, Fisher Steve, Garfin Steven R, Gogia Jaspaul S, Gokaslan Ziya L, Kuo Calvin C, Lee Yu-Po, Mavrommatis Konstantinos, Michu Elleni, Noskova Hana, Raz Assaf, Sana Jiri, Shamie A Nick, Stewart Philip S, Stonemetz Jerry L, Wang Jeffrey C, Witham Timothy F, Coscia Michael F, Birkenmaier Christof, Fischetti Vincent A, Slaby Ondrej

Streptococcus pyogenes Sortase Mutants Are Highly Susceptible to Killing by Host Factors Due to Aberrant Envelope Physiology

由于包膜生理异常,化脓性链球菌分选酶突变体极易被宿主因子杀死。

Raz, Assaf; Tanasescu, Ana-Maria; Zhao, Anna M; Serrano, Anna; Alston, Tricia; Sol, Asaf; Bachrach, Gilad; Fischetti, Vincent A

A highly active and negatively charged Streptococcus pyogenes lysin with a rare D-alanyl-L-alanine endopeptidase activity protects mice against streptococcal bacteremia

一种具有罕见的D-丙氨酰-L-丙氨酸内肽酶活性的高活性带负电荷的化脓性链球菌溶素可保护小鼠免受链球菌菌血症的感染。

Lood, Rolf; Raz, Assaf; Molina, Henrik; Euler, Chad W; Fischetti, Vincent A