MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM
MM-131 是一种双特异性抗 Met/EpCAM mAb,通过同时结合 EpCAM 来抑制 HGF 依赖性和 HGF 非依赖性的 Met 信号传导
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:
doi:10.1073/pnas.1819085116
Jessica B Casaletto, Melissa L Geddie, Adnan O Abu-Yousif, Kristina Masson, Aaron Fulgham, Antoine Boudot, Tim Maiwald, Jeffrey D Kearns, Neeraj Kohli, Stephen Su, Maja Razlog, Andreas Raue, Ashish Kalra, Maria Håkansson, Derek T Logan, Martin Welin, Shrikanta Chattopadhyay, Brian D Harms, Ulrik B N