日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Fatty acids and albumin are transported by distinct mechanisms in the proximal tubule

脂肪酸和白蛋白在近端小管中通过不同的机制进行运输。

Garcia, Nestor H; Gaivin, Robert J; Khan, Shenaz; Li, Vincent; Rbaibi, Youssef; Weisz, Ora A; Garvin, Jeffrey L; Schelling, Jeffrey R

SGLT2-independent effects of canagliflozin on NHE3 and mitochondrial complex I activity inhibit proximal tubule fluid transport and albumin uptake.

卡格列净对 NHE3 和线粒体复合物 I 活性的 SGLT2 非依赖性作用可抑制近端肾小管液体转运和白蛋白吸收

Albalawy Wafaa N, Youm Elynna B, Shipman Katherine E, Trull Keelan J, Baty Catherine J, Long Kimberly R, Rbaibi Youssef, Wang Xue-Ping, Fagunloye Olayemi G, White Katharine A, Jurczak Michael J, Kashlan Ossama B, Weisz Ora A

Megalin Knockout Reduces SGLT2 Expression and Sensitizes to Western Diet-induced Kidney Injury

Megalin 基因敲除可降低 SGLT2 表达并对西方饮食引起的肾损伤敏感

Elynna B Youm, Katherine E Shipman, Wafaa N Albalawy, Amber M Vandevender, Ian J Sipula, Youssef Rbaibi, Allison E Marciszyn, Jared A Lashway, Emma E Brown, Corry B Bondi, Cary R Boyd-Shiwarski, Roderick J Tan, Michael J Jurczak, Ora A Weisz

Impaired Endosome Maturation Mediates Tubular Proteinuria in Dent Disease Cell Culture and Mouse Models

内体成熟受损介导牙本质病细胞培养和小鼠模型中的肾小管蛋白尿

Katherine E Shipman, Catherine J Baty, Kimberly R Long, Youssef Rbaibi, Isabella A Cowan, Mona Gerges, Allison L Marciszyn, Ossama B Kashlan, Roderick J Tan, Aurélie Edwards, Ora A Weisz

Receptor-associated protein impairs ligand binding to megalin and megalin-dependent endocytic flux in proximal tubule cells.

受体相关蛋白会损害配体与巨蛋白的结合以及近端肾小管细胞中巨蛋白依赖的内吞作用

Long Kimberly R, Rbaibi Youssef, Kashlan Ossama B, Weisz Ora A

Megalin, cubilin, and Dab2 drive endocytic flux in kidney proximal tubule cells

Megalin、cubilin 和 Dab2 驱动肾脏近端小管细胞的内吞通量

Youssef Rbaibi, Kimberly R Long, Katherine E Shipman, Qidong Ren, Catherine J Baty, Ossama B Kashlan, Ora A Weisz

Cubilin-, megalin-, and Dab2-dependent transcription revealed by CRISPR/Cas9 knockout in kidney proximal tubule cells

CRISPR/Cas9 敲除揭示肾脏近端小管细胞中 Cubilin、megalin 和 Dab2 依赖性转录

Kimberly R Long, Youssef Rbaibi, Corry D Bondi, B Rhodes Ford, Amanda C Poholek, Cary R Boyd-Shiwarski, Roderick J Tan, Joseph D Locker, Ora A Weisz

An Adaptable Physiological Model of Endocytic Megalin Trafficking in Opossum Kidney Cells and Mouse Kidney Proximal Tubule

负鼠肾细胞和小鼠肾近端小管内吞巨蛋白运输的适应性生理模型

Katherine E Shipman, Kimberly R Long, Isabella A Cowan, Youssef Rbaibi, Catherine J Baty, Ora A Weisz

Effects of Proximal Tubule Shortening on Protein Excretion in a Lowe Syndrome Model

近端小管缩短对 Lowe 综合征模型中蛋白质排泄的影响

Megan L Gliozzi, Eugenel B Espiritu, Katherine E Shipman, Youssef Rbaibi, Kimberly R Long, Nairita Roy, Andrew W Duncan, Matthew J Lazzara, Neil A Hukriede, Catherine J Baty, Ora A Weisz

Distinct functions of megalin and cubilin receptors in recovery of normal and nephrotic levels of filtered albumin

巨蛋白和立方体蛋白受体在恢复正常和肾病水平滤过白蛋白方面发挥着不同的作用

Qidong Ren, Kathrin Weyer, Youssef Rbaibi, Kimberly R Long, Roderick J Tan, Rikke Nielsen, Erik I Christensen, Catherine J Baty, Ossama B Kashlan, Ora A Weisz