日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Characterising the Transcriptomic Response to Interferon and Infection in European Domestic Ferret Respiratory Tissues Using Long-Read RNA Sequencing

利用长读长RNA测序技术表征欧洲家养雪貂呼吸道组织对干扰素和感染的转录组反应

Farrukee, Rubaiyea; Chang, Jessie J-Y; Zhang, Jianshu; Barnes, James B; Zhang, Shu Xin; Tan, Sher Maine; Reading, Patrick C; Coin, Lachlan J M

Safety and Immunogenicity of a Severe Acute Respiratory Syndrome Coronavirus 2 Spike Subunit Vaccine Stabilized in the Prefusion Conformation by a Second-Generation Molecular Clamp and Evaluated in Adults Aged 18-55 Years: A Randomized, Double-Blind, Active Comparator, Phase I Trial

利用第二代分子钳技术稳定融合前构象的严重急性呼吸综合征冠状病毒2刺突蛋白亚单位疫苗在18-55岁成年人中的安全性和免疫原性:一项随机、双盲、活性对照的I期试验

Chappell, Keith J; Mordant, Francesca L; Amarilla, Alberto A; Modhiran, Naphak; Liang, Benjamin; Li, Zheyi; Lackenby, Julia A; Jaberolansar, Noushin; O'Donnell, Jake; Kienzle, Vivian; Kommajosyula, Varsha; Tardiota, Nicolas; Bennet, Jillian K; Henderson, Christina L; Dalrymple, Rhiannon L; Goh, Justin; Hoger, Kym; Gillard, Marianne; Jones, Martina L; Hughes, Karen; Hughes, Ben; Barnes, James; Reading, Patrick C; Ranasinghe, Charani; Subbarao, Kanta; Munro, Trent P; Young, Paul R; Watterson, Daniel

Host restriction factor SAMHD1 does not restrict seasonal influenza virus replication in human epithelial or macrophage-like cells

宿主限制因子SAMHD1并不限制季节性流感病毒在人上皮细胞或巨噬细胞样细胞中的复制。

Xia, Yongyan; Farrukee, Rubaiyea; Brooks, Andrew G; Soler, Sofía; Behrendt, Rayk; Bartok, Eva; Londrigan, Sarah L; Reading, Patrick C

The E3 ubiquitin ligase MARCHF8 restricts HSV-1 infection by inhibiting replication of the viral genome

E3泛素连接酶MARCHF8通过抑制病毒基因组的复制来限制HSV-1感染。

Xia, Yongyan; Nigos, L Rayburn; Villalón-Letelier, Fernando; Tessema, Melkamu B; Brooks, Andrew G; Bartok, Eva; Behrendt, Rayk; Londrigan, Sarah L; Reading, Patrick C; Farrukee, Rubaiyea

Long-term safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18-55 years or ≥56 years: 12-month results from a randomised, double-blind, placebo-controlled, phase 1 trial

一项针对18-55岁或≥56岁成年人的随机、双盲、安慰剂对照I期临床试验的12个月结果显示,MF59佐剂增强的SARS-CoV-2刺突糖蛋白钳疫苗具有长期安全性和免疫原性。

Chappell, Keith J; Mordant, Francesca L; Amarilla, Alberto A; Modhiran, Naphak; Liang, Benjamin; Li, Zheyi; Wijesundara, Danushka K; Lackenby, Julia A; Griffin, Paul; Bennet, Jillian K; Hensen, Luca; Zhang, Wuji; Nguyen, Thi H O; Tran, Mai H; Tapley, Peter; Barnes, James; Reading, Patrick C; Kedzierska, Katherine; Ranasinghe, Charani; Subbarao, Kanta; Watterson, Daniel; Young, Paul R; Munro, Trent P

Characterization and comparison of novel adjuvants for a prefusion clamped MERS vaccine.

对用于预融合钳制MERS疫苗的新型佐剂进行表征和比较

O'Donnell Jake S, Isaacs Ariel, Jakob Virginie, Lebas Celia, Barnes James B, Reading Patrick C, Young Paul R, Watterson Daniel, Dubois Patrice M, Collin Nicolas, Chappell Keith J

Retinoic Acid-Inducible Gene I Activation Inhibits Human Respiratory Syncytial Virus Replication in Mammalian Cells and in Mouse and Ferret Models of Infection

视黄酸诱导基因I激活抑制人呼吸道合胞病毒在哺乳动物细胞以及小鼠和雪貂感染模型中的复制

Schwab, Lara S U; Farrukee, Rubaiyea; Eléouët, Jean-François; Rameix-Welti, Marie-Anne; Londrigan, Sarah L; Brooks, Andrew G; Hurt, Aeron C; Coch, Christoph; Zillinger, Thomas; Hartmann, Gunther; Reading, Patrick C

Infection with different human influenza A subtypes affects the period of susceptibility to secondary bacterial infections in ferrets

感染不同亚型的人类甲型流感病毒会影响雪貂对继发性细菌感染的易感期。

Mifsud, Edin J; Farrukee, Rubaiyea; Hurt, Aeron C; Reading, Patrick C; Barr, Ian G

Predicting Permissive Mutations That Improve the Fitness of A(H1N1)pdm09 Viruses Bearing the H275Y Neuraminidase Substitution

预测可提高携带 H275Y 神经氨酸酶突变的 A(H1N1)pdm09 病毒适应性的容许突变

Farrukee, Rubaiyea; Gunalan, Vithiagaran; Maurer-Stroh, Sebastian; Reading, Patrick C; Hurt, Aeron C

Mouse Mx1 Inhibits Herpes Simplex Virus Type 1 Genomic Replication and Late Gene Expression In Vitro and Prevents Lesion Formation in the Mouse Zosteriform Model

小鼠Mx1在体外抑制1型单纯疱疹病毒基因组复制和晚期基因表达,并阻止小鼠带状疱疹模型中病变的形成。

Tessema, Melkamu B; Farrukee, Rubaiyea; Andoniou, Christopher E; Degli-Esposti, Mariapia A; Oates, Clare V; Barnes, James B; Wakim, Linda M; Brooks, Andrew G; Londrigan, Sarah L; Reading, Patrick C