Inhibition of RNA splicing triggers CHMP7 nuclear entry, impacting TDP-43 function and leading to the onset of ALS cellular phenotypes.
RNA剪接抑制会触发CHMP7进入细胞核，影响TDP-43的功能，从而导致ALS细胞表型的出现
期刊:Neuron
影响因子:15
doi:10.1016/j.neuron.2024.10.007
Al-Azzam Norah, To Jenny H, Gautam Vaishali, Street Lena A, Nguyen Chloe B, Naritomi Jack T, Lam Dylan C, Madrigal Assael A, Lee Benjamin, Jin Wenhao, Avina Anthony, Mizrahi Orel, Mueller Jasmine R, Ford Willard, Schiavon Cara R, Rebollo Elena, Vu Anthony Q, Blue Steven M, Madakamutil Yashwin L, Manor Uri, Rothstein Jeffrey D, Coyne Alyssa N, Jovanovic Marko, Yeo Gene W
