日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanism of DNA degradation by CBASS Cap5 endonuclease immune effector

CBASS Cap5 内切酶免疫效应物降解 DNA 的机制

Rechkoblit, Olga; Sciaky, Daniela; Ni, Mi; Li, Yangmei; Kottur, Jithesh; Fang, Gang; Aggarwal, Aneel K

Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides

环核苷酸激活CBASS Cap5核酸内切酶免疫效应物

Rechkoblit, Olga; Sciaky, Daniela; Kreitler, Dale F; Buku, Angeliki; Kottur, Jithesh; Aggarwal, Aneel K

Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals

SARS-CoV-2 N7-甲基转移酶与DOT1L和PRMT7抑制剂的结构为新型抗病毒药物的研发提供了平台

Kottur, Jithesh; White, Kris M; Rodriguez, M Luis; Rechkoblit, Olga; Quintana-Feliciano, Richard; Nayar, Ahana; García-Sastre, Adolfo; Aggarwal, Aneel K

High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development

SARS-CoV-2 N7-甲基转移酶的高分辨率结构为治疗药物的研发提供信息

Kottur, Jithesh; Rechkoblit, Olga; Quintana-Feliciano, Richard; Sciaky, Daniela; Aggarwal, Aneel K

Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase

人类PrimPol引物酶-聚合酶对8-氧鸟嘌呤的DNA合成的结构基础

Rechkoblit, Olga; Johnson, Robert E; Gupta, Yogesh K; Prakash, Louise; Prakash, Satya; Aggarwal, Aneel K

Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease

108600 同时抑制 CK2/TNIK/DYRK1 可抑制三阴性乳腺癌干细胞和化疗耐药性疾病

Katsutoshi Sato #, Amol A Padgaonkar #, Stacey J Baker, Stephen C Cosenza, Olga Rechkoblit, D R C Venkata Subbaiah, Josep Domingo-Domenech, Alison Bartkowski, Elisa R Port, Aneel K Aggarwal, M V Ramana Reddy, Hanna Y Irie, E Premkumar Reddy

Structural insights into mutagenicity of anticancer nucleoside analog cytarabine during replication by DNA polymerase η

抗癌核苷类似物阿糖胞苷在DNA聚合酶η复制过程中的诱变性结构研究

Rechkoblit, Olga; Johnson, Robert E; Buku, Angeliki; Prakash, Louise; Prakash, Satya; Aggarwal, Aneel K

Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy

顺铂DNA损伤耐受性的结构基础:人类聚合酶η在癌症化疗中的作用

Ummat, Ajay; Rechkoblit, Olga; Jain, Rinku; Roy Choudhury, Jayati; Johnson, Robert E; Silverstein, Timothy D; Buku, Angeliki; Lone, Samer; Prakash, Louise; Prakash, Satya; Aggarwal, Aneel K

Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4

Y家族聚合酶Dpo4无错半靶向诱变绕过芳香胺损伤的机制

Rechkoblit, Olga; Kolbanovskiy, Alexander; Malinina, Lucy; Geacintov, Nicholas E; Broyde, Suse; Patel, Dinshaw J

DNA adduct structure-function relationships: comparing solution with polymerase structures

DNA加合物结构-功能关系:溶液结构与聚合酶结构的比较

Broyde, Suse; Wang, Lihua; Zhang, Ling; Rechkoblit, Olga; Geacintov, Nicholas E; Patel, Dinshaw J