Inhibition of PIM kinase in tumor associated macrophages suppresses inflammasome activation and sensitizes prostate cancer to immunotherapy
抑制肿瘤相关巨噬细胞中的PIM激酶可抑制炎症小体活化,并使前列腺癌对免疫疗法更加敏感。
期刊:
影响因子:
doi:10.1101/2024.10.21.618756
Clements, Amber N; Casillas, Andrea L; Flores, Caitlyn E; Liou, Hope; Toth, Rachel K; Chauhan, Shailender S; Sutterby, Kai; Deshmukh, Sachin Kumar; Wu, Sharon; Xiu, Joanne; Farrell, Alex; Radovich, Milan; Nabhan, Chadi; Heath, Elisabeth I; McKay, Rana R; Subah, Noor; Centuori, Sara; Wheeler, Travis J; Cress, Anne E; Rogers, Gregory C; Wilson, Justin E; Recio-Boiles, Alejandro; Warfel, Noel A
细胞生物学
肿瘤
巨噬细胞
炎性小体
炎性小体
前列腺癌
免疫/内分泌
肿瘤免疫
巨噬细胞
信号转导
炎症
炎症/感染