日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Modulation of cytomegalovirus immune evasion identifies direct antigen presentation as the predominant mode of CD8 T-cell priming during immune reconstitution after hematopoietic cell transplantation

巨细胞病毒免疫逃避的调节确定直接抗原呈递是造血细胞移植后免疫重建过程中 CD8 T 细胞启动的主要方式

Rafaela Holtappels, Julia K Büttner, Kirsten Freitag, Matthias J Reddehase, Niels A Lemmermann

Cytomegalovirus inhibitors of programmed cell death restrict antigen cross-presentation in the priming of antiviral CD8 T cells

程序性细胞死亡的巨细胞病毒抑制剂限制抗病毒 CD8 T 细胞启动中的抗原交叉呈递

Stefan Ebert, Verena Böhm, Julia K Büttner, Wolfram Brune, Melanie M Brinkmann, Rafaela Holtappels, Matthias J Reddehase, Niels A W Lemmermann

Direct antigen presentation is the canonical pathway of cytomegalovirus CD8 T-cell priming regulated by balanced immune evasion ensuring a strong antiviral response

直接抗原呈递是巨细胞病毒 CD8 T 细胞启动的典型途径,受平衡免疫逃避调节,确保强大的抗病毒反应

Julia K Büttner, Sara Becker, Annette Fink, Melanie M Brinkmann, Rafaela Holtappels, Matthias J Reddehase, Niels A Lemmermann

Immunotherapy of cytomegalovirus infection by low-dose adoptive transfer of antiviral CD8 T cells relies on substantial post-transfer expansion of central memory cells but not effector-memory cells

低剂量过继转移抗病毒CD8 T细胞治疗巨细胞病毒感染的免疫疗法依赖于转移后中央记忆细胞的大量扩增,而非效应记忆细胞的扩增。

Holtappels, Rafaela; Becker, Sara; Hamdan, Sara; Freitag, Kirsten; Podlech, Jürgen; Lemmermann, Niels A; Reddehase, Matthias J

Cytomegalovirus immune evasion sets the functional avidity threshold for protection by CD8 T cells

巨细胞病毒的免疫逃逸决定了CD8 T细胞保护作用的功能性亲和力阈值。

Hamdan, Sara; Reddehase, Matthias J; Holtappels, Rafaela

Host-Adapted Gene Families Involved in Murine Cytomegalovirus Immune Evasion

参与小鼠巨细胞病毒免疫逃逸的宿主适应性基因家族

Becker, Sara; Fink, Annette; Podlech, Jürgen; Reddehase, Matthias J; Lemmermann, Niels A

Memory CD8 T Cells Protect against Cytomegalovirus Disease by Formation of Nodular Inflammatory Foci Preventing Intra-Tissue Virus Spread

记忆性CD8 T细胞通过形成结节性炎症灶来抵抗巨细胞病毒感染,从而阻止病毒在组织内扩散。

Holtappels, Rafaela; Podlech, Jürgen; Freitag, Kirsten; Lemmermann, Niels A; Reddehase, Matthias J

Therapeutic Vaccination of Hematopoietic Cell Transplantation Recipients Improves Protective CD8 T-Cell Immunotherapy of Cytomegalovirus Infection

造血干细胞移植受者接受治疗性疫苗接种可增强巨细胞病毒感染的保护性CD8 T细胞免疫疗法

Gergely, Kerstin M; Podlech, Jürgen; Becker, Sara; Freitag, Kirsten; Krauter, Steffi; Büscher, Nicole; Holtappels, Rafaela; Plachter, Bodo; Reddehase, Matthias J; Lemmermann, Niels A W

Stochastic Episodes of Latent Cytomegalovirus Transcription Drive CD8 T-Cell "Memory Inflation" and Avoid Immune Evasion

潜伏性巨细胞病毒转录的随机事件驱动 CD8 T 细胞“记忆膨胀”并避免免疫逃避

Marion Griessl, Angelique Renzaho, Kirsten Freitag, Christof K Seckert, Matthias J Reddehase, Niels A W Lemmermann

Cortical representation of experimental periodontal pain: a functional magnetic resonance imaging study

实验性牙周疼痛的皮层表征:一项功能磁共振成像研究

Maurer, Angelika; Verma, Damian; Reddehase, Annika; Scheef, Lukas; Radbruch, Alexander; Attenberger, Ulrike; Jäger, Andreas; Boecker, Henning