日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immunotherapy of cytomegalovirus infection by low-dose adoptive transfer of antiviral CD8 T cells relies on substantial post-transfer expansion of central memory cells but not effector-memory cells

低剂量过继转移抗病毒CD8 T细胞治疗巨细胞病毒感染的免疫疗法依赖于转移后中央记忆细胞的大量扩增,而非效应记忆细胞的扩增。

Holtappels, Rafaela; Becker, Sara; Hamdan, Sara; Freitag, Kirsten; Podlech, Jürgen; Lemmermann, Niels A; Reddehase, Matthias J

Cytomegalovirus immune evasion sets the functional avidity threshold for protection by CD8 T cells

巨细胞病毒的免疫逃逸决定了CD8 T细胞保护作用的功能性亲和力阈值。

Hamdan, Sara; Reddehase, Matthias J; Holtappels, Rafaela

Host-Adapted Gene Families Involved in Murine Cytomegalovirus Immune Evasion

参与小鼠巨细胞病毒免疫逃逸的宿主适应性基因家族

Becker, Sara; Fink, Annette; Podlech, Jürgen; Reddehase, Matthias J; Lemmermann, Niels A

Memory CD8 T Cells Protect against Cytomegalovirus Disease by Formation of Nodular Inflammatory Foci Preventing Intra-Tissue Virus Spread

记忆性CD8 T细胞通过形成结节性炎症灶来抵抗巨细胞病毒感染,从而阻止病毒在组织内扩散。

Holtappels, Rafaela; Podlech, Jürgen; Freitag, Kirsten; Lemmermann, Niels A; Reddehase, Matthias J

Therapeutic Vaccination of Hematopoietic Cell Transplantation Recipients Improves Protective CD8 T-Cell Immunotherapy of Cytomegalovirus Infection

造血干细胞移植受者接受治疗性疫苗接种可增强巨细胞病毒感染的保护性CD8 T细胞免疫疗法

Gergely, Kerstin M; Podlech, Jürgen; Becker, Sara; Freitag, Kirsten; Krauter, Steffi; Büscher, Nicole; Holtappels, Rafaela; Plachter, Bodo; Reddehase, Matthias J; Lemmermann, Niels A W

Immunodominant Cytomegalovirus Epitopes Suppress Subdominant Epitopes in the Generation of High-Avidity CD8 T Cells

免疫优势巨细胞病毒表位抑制亚优势表位,从而促进高亲和力CD8 T细胞的生成

Freitag, Kirsten; Hamdan, Sara; Reddehase, Matthias J; Holtappels, Rafaela

Positive Role of the MHC Class-I Antigen Presentation Regulator m04/gp34 of Murine Cytomegalovirus in Antiviral Protection by CD8 T Cells

小鼠巨细胞病毒MHC I类抗原呈递调节因子m04/gp34在CD8 T细胞抗病毒保护中的积极作用

Becker, Sara; Fink, Annette; Podlech, Jürgen; Giese, Irina; Schmiedeke, Julia K; Bukur, Thomas; Reddehase, Matthias J; Lemmermann, Niels A

The Anti-apoptotic Murine Cytomegalovirus Protein vMIA-m38.5 Induces Mast Cell Degranulation

抗凋亡鼠巨细胞病毒蛋白vMIA-m38.5诱导肥大细胞脱颗粒

Schmiedeke, Julia K; Hartmann, Ann-Kathrin; Ruckenbrod, Teresa; Stassen, Michael; Reddehase, Matthias J; Lemmermann, Niels A

Cytomegalovirus-Associated Inhibition of Hematopoiesis Is Preventable by Cytoimmunotherapy With Antiviral CD8 T Cells

巨细胞病毒相关的造血抑制可通过抗病毒CD8 T细胞的细胞免疫疗法预防

Renzaho, Angelique; Podlech, Jürgen; Kühnapfel, Birgit; Blaum, Franziska; Reddehase, Matthias J; Lemmermann, Niels A W

Enhancement of Antigen Presentation by Deletion of Viral Immune Evasion Genes Prevents Lethal Cytomegalovirus Disease in Minor Histocompatibility Antigen-Mismatched Hematopoietic Cell Transplantation

通过删除病毒免疫逃逸基因增强抗原呈递,可预防次要组织相容性抗原不匹配的造血干细胞移植中致命的巨细胞病毒疾病。

Gezinir, Emin; Podlech, Jürgen; Gergely, Kerstin M; Becker, Sara; Reddehase, Matthias J; Lemmermann, Niels A W