Tigilanol tiglate is an oncolytic small molecule that induces immunogenic cell death and enhances the response of both target and non-injected tumors to immune checkpoint blockade
替吉拉诺替格酸酯是一种溶瘤小分子,可诱导免疫原性细胞死亡,并增强靶肿瘤和非注射肿瘤对免疫检查点阻断的反应。
期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2022-006602
Cullen, Jason K; Yap, Pei-Yi; Ferguson, Blake; Bruce, Zara C; Koyama, Motoko; Handoko, Herlina; Hendrawan, Kevin; Simmons, Jacinta L; Brooks, Kelly M; Johns, Jenny; Wilson, Emily S; de Souza, Marjorie M A; Broit, Natasa; Stewart, Praphaporn; Shelley, Daniel; McMahon, Tracey; Ogbourne, Steven M; Nguyen, Tam Hong; Lim, Yi Chieh; Pagani, Alberto; Appendino, Giovanni; Gordon, Victoria A; Reddell, Paul W; Boyle, Glen M; Parsons, Peter G