日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Epoxytiglianes potentiate the activity of colistin against resistant Escherichia coli via modification of the bacterial cell membrane

环氧替利烷类化合物通过修饰细菌细胞膜,增强粘菌素对耐药性大肠杆菌的活性。

Pritchard, Manon F; Xue, Wenya; Wu, Jingxiang; Boardman, Francesca; Li, Mei; Zhou, Yuqing; Khan, Saira; Powell, Lydia C; Stokniene, Joana; Davies-Jones, Josh; Davies, Philip R; Buurma, Niklaas J; Menzies, Georgina E; Spiller, Owen B; Walsh, Timothy R; Reddell, Paul; Hill, Katja E; Thomas, David W

Intratumoural tigilanol tiglate in the multicentre treatment of equine sarcoids and cutaneous melanomas

在多中心治疗马肉瘤和皮肤黑色素瘤中,瘤内注射替吉拉诺替格酯

Labens, Raphael; Saba, Corey; Williams, Jarred; Hollis, Anna; Ensink, Jos; Jose-Cunilleras, Eduard; Jordana-Garcia, Mireia; Bergvall, Kerstin; Ruppin, Mick; Condon, Frank; Spelta, Caroline; Elce, Yvonne; De Ridder, Thomas; Morton, John; McGee, Cassandra; Reddell, Paul

Tigilanol tiglate is an oncolytic small molecule that induces immunogenic cell death and enhances the response of both target and non-injected tumors to immune checkpoint blockade

替吉拉诺替格酸酯是一种溶瘤小分子,可诱导免疫原性细胞死亡,并增强靶肿瘤和非注射肿瘤对免疫检查点阻断的反应。

Cullen, Jason K; Yap, Pei-Yi; Ferguson, Blake; Bruce, Zara C; Koyama, Motoko; Handoko, Herlina; Hendrawan, Kevin; Simmons, Jacinta L; Brooks, Kelly M; Johns, Jenny; Wilson, Emily S; de Souza, Marjorie M A; Broit, Natasa; Stewart, Praphaporn; Shelley, Daniel; McMahon, Tracey; Ogbourne, Steven M; Nguyen, Tam Hong; Lim, Yi Chieh; Pagani, Alberto; Appendino, Giovanni; Gordon, Victoria A; Reddell, Paul W; Boyle, Glen M; Parsons, Peter G

Tigilanol Tiglate-Induced Changes in Secretome Profiles Alter C-Met Phosphorylation and Cell Surface Protein Expression in H357 Head and Neck Cancer Cells

替吉拉醇替格酯诱导的分泌蛋白组谱变化改变了 H357 头颈癌细胞中的 C-Met 磷酸化和细胞表面蛋白表达

Frank Dickson Antwi, Tufaha Awad, Meghan Larin, Kate Heesom, Phil Lewis, Paul Reddell, Zaruhi Poghosyan, Sharon Dewitt, Ryan Moseley, Vera Knäuper

Defining in vitro topical antimicrobial and antibiofilm activity of epoxy-tigliane structures against oral pathogens

体外测定环氧-虎基烷结构对口腔病原体的局部抗菌和抗生物膜活性

Xue, Wenya; Pritchard, Manon F; Khan, Saira; Powell, Lydia C; Stokniene, Joana; Wu, Jingxiang; Claydon, Nicholas; Reddell, Paul; Thomas, David W; Hill, Katja E

High Resolution Multiplex Confocal Imaging of the Neurovascular Unit in Health and Experimental Ischemic Stroke

健康和实验性缺血性中风的神经血管单元的高分辨率多重共聚焦成像

Jeffrey J Lochhead, Erica I Williams, Elizabeth S Reddell, Emma Dorn, Patrick T Ronaldson, Thomas P Davis

Psychosocial functioning mediates change in motor and cognitive function throughout neurorehabilitation for adults with acquired brain injury (ABI-RESTaRT)

心理社会功能在获得性脑损伤成人神经康复过程中调节运动和认知功能的变化(ABI-RESTaRT)

Mann, Georgina; Troeung, Lakkhina; Singh, Krishneil A; Reddell, Curtis; Martini, Angelita

High-Dose Acetaminophen Alters the Integrity of the Blood-Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats

高剂量的对乙酰氨基酚会改变大鼠血脑屏障的完整性,导致中枢神经系统对可待因的吸收增加

Junzhi Yang, Robert D Betterton, Erica I Williams, Joshua A Stanton, Elizabeth S Reddell, Chidinma E Ogbonnaya, Emma Dorn, Thomas P Davis, Jeffrey J Lochhead, Patrick T Ronaldson

Regulation of Blood-Brain Barrier Transporters by Transforming Growth Factor- β/Activin Receptor-Like Kinase 1 Signaling: Relevance to the Brain Disposition of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors (i.e., Statins)

转化生长因子-β/促活素受体样激酶 1 信号对血脑屏障转运蛋白的调节:与 3-羟基-3-甲基戊二酰辅酶 A 还原酶抑制剂(即他汀类药物)的脑分布的相关性

Robert D Betterton, Wazir Abdullahi, Erica I Williams, Jeffrey J Lochhead, Hrvoje Brzica, Joshua Stanton, Elizabeth Reddell, Chidinma Ogbonnaya, Thomas P Davis, Patrick T Ronaldson

Treatment of multiple synchronous canine mast cell tumours using intratumoural tigilanol tiglate

使用瘤内注射替吉拉诺替格酯治疗犬多发性同步肥大细胞瘤

Brown, Graham K; Finlay, Jessica R; Straw, Rodney C; Ziea, Joy Y; Leung, Becky; O'Connell, Kathleen; Thomson, Maurine J; Campbell, Justine E; Jones, Pamela D; Reddell, Paul