日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genome-Wide Histone Acetylation Underlies Tumor Intrinsic Immune Signaling Induced by Photothermal Therapy in Ovarian Cancer

全基因组组蛋白乙酰化是卵巢癌光热疗法诱导肿瘤内在免疫信号传导的基础

Walker, Reddick R; Hadley, Melissa; Colina, Jose; Nestler, Kevin; Lee, Abigail V; Sweeney, Elizabeth E; Fernandes, Rohan; Chiappinelli, Katherine B

Differential modulation of cellular phenotype and drug sensitivity by extracellular matrix proteins in primary and metastatic pancreatic cancer cells

原发性和转移性胰腺癌细胞中细胞外基质蛋白对细胞表型和药物敏感性的差异调节

Olalekan H Usman, Sampath Kumar, Reddick R Walker 3rd, Gengqiang Xie, Hyeje C Sumajit, AbdelAziz R Jalil, Subramanian Ramakrishnan, Lawrence J Dooling, Yue Julia Wang, Jerome Irianto

Epigenetically programmed resistance to chemo- and immuno-therapies

表观遗传编程导致的化疗和免疫疗法耐药性

Walker, Reddick R; Rentia, Zainab; Chiappinelli, Katherine B

MEDB-81. Combined inhibition of CDK11 and EZH2 results in regression of MYC-amplified medulloblastoma

MEDB-81。CDK11 和 EZH2 的联合抑制可导致 MYC 扩增型髓母细胞瘤消退。

Hodgin, J B; Krege, J H; Reddick, R L; Korach, K S; Smithies, O; Maeda, N; Wang, Dong; Veo, Bethany; Pierce, Angela; Venkataraman, Sujatha; Vibhakar, Rajeev

Inhibiting DNA methylation and RNA editing upregulates immunogenic RNA to transform the tumor microenvironment and prolong survival in ovarian cancer

抑制DNA甲基化和RNA编辑可上调免疫原性RNA,从而改变肿瘤微环境并延长卵巢癌患者的生存期。

Stephanie Gomez ,Olivia L Cox ,Reddick R Walker 3rd ,Uzma Rentia ,Melissa Hadley ,Elisa Arthofer ,Noor Diab ,Erin E Grundy ,Tomas Kanholm ,James I McDonald ,Julie Kobyra ,Erica Palmer ,Satish Noonepalle ,Alejandro Villagra ,David Leitenberg ,Catherine M Bollard ,Yogen Saunthararajah ,Katherine B Chiappinelli

Hematopoietic knockdown of PPARδ reduces atherosclerosis in LDLR-/- mice

造血系统敲低PPARδ可减轻LDLR-/-小鼠的动脉粥样硬化

Li, G; Chen, C; Laing, S D; Ballard, C; Biju, K C; Reddick, R L; Clark, R A; Li, S

Critical role of chemokine (C-C motif) receptor 2 (CCR2) in the KKAy + Apoe -/- mouse model of the metabolic syndrome

趋化因子(CC基序)受体2(CCR2)在KKAy+Apoe-/-代谢综合征小鼠模型中的关键作用

Martinez, H G; Quinones, M P; Jimenez, F; Estrada, C A; Clark, K; Muscogiuri, G; Sorice, G; Musi, N; Reddick, R L; Ahuja, S S

Spontaneous hepatocellular carcinoma is reduced in transgenic mice overexpressing human O6- methylguanine-DNA methyltransferase

在过表达人O6-甲基鸟嘌呤-DNA甲基转移酶的转基因小鼠中,自发性肝细胞癌的发生率降低。

Zhou, Z Q; Manguino, D; Kewitt, K; Intano, G W; McMahan, C A; Herbert, D C; Hanes, M; Reddick, R; Ikeno, Y; Walter, C A

CC chemokine receptor (CCR)2 is required for langerhans cell migration and localization of T helper cell type 1 (Th1)-inducing dendritic cells. Absence of CCR2 shifts the Leishmania major-resistant phenotype to a susceptible state dominated by Th2 cytokines, b cell outgrowth, and sustained neutrophilic inflammation

CC趋化因子受体2 (CCR2) 是朗格汉斯细胞迁移和诱导1型辅助性T细胞 (Th1) 的树突状细胞定位所必需的。CCR2的缺失会使对利什曼原虫具有抵抗力的表型转变为易感状态,这种状态以Th2细胞因子、B细胞增殖和持续性中性粒细胞炎症为主。

Sato, N; Ahuja, S K; Quinones, M; Kostecki, V; Reddick, R L; Melby, P C; Kuziel, W A; Ahuja, S S

Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A

缺乏利钠肽受体A的小鼠出现高血压、心脏肥大和猝死。

Oliver, P M; Fox, J E; Kim, R; Rockman, H A; Kim, H S; Reddick, R L; Pandey, K N; Milgram, S L; Smithies, O; Maeda, N