日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Unlocking the therapeutic potential of rigosertib as a selective therapy for ovarian cancer.

释放利戈塞替尼作为卵巢癌选择性疗法的治疗潜力

Nath Shalini, Claridge Sally, Granados Genesis Lara, Al Assaad Majd, Park Eric, Cavallo Julie-Ann, Nuwere Ufuoma, Ackon Maame Esi, De Boni Lamberto, Baker Stacey, Reddy E Premkumar, Blank Stephanie V, Elemento Olivier, Brody Rachel, Hopkins Benjamin D

A Drosophila model for Costello Syndrome caused by Ras mutation K117R

由 Ras 基因 K117R 突变引起的 Costello 综合征的果蝇模型

Karunaraj, Prashath; Cao, Emily; Singh, Harnoor; Luf, Max; Baker, Stacey J; Reddy, E Premkumar; Pfleger, Cathie M

CDK4: a master regulator of the cell cycle and its role in cancer

CDK4:细胞周期的主要调控因子及其在癌症中的作用

Baker, Stacey J; Poulikakos, Poulikos I; Irie, Hanna Y; Parekh, Samir; Reddy, E Premkumar

Rigosertib ameliorates the effects of oncogenic KRAS signaling in a murine model of myeloproliferative neoplasia

Rigosertib 改善了小鼠骨髓增生性肿瘤模型中致癌 KRAS 信号的影响

Stacey J Baker, Stephen C Cosenza, M V Ramana Reddy, E Premkumar Reddy

Drugging the 'undruggable' cancer targets

针对“不可成药”癌症靶点的药物治疗

Dang, Chi V; Reddy, E Premkumar; Shokat, Kevan M; Soucek, Laura

JNK-signaling: A multiplexing hub in programmed cell death

JNK信号通路:程序性细胞死亡中的多重枢纽

Dhanasekaran, Danny N; Reddy, E Premkumar

Aberrant expression of JNK-associated leucine-zipper protein, JLP, promotes accelerated growth of ovarian cancer

JNK相关亮氨酸拉链蛋白(JLP)的异常表达促进卵巢癌的加速生长

Ha, Ji Hee; Yan, Mingda; Gomathinayagam, Rohini; Jayaraman, Muralidharan; Husain, Sanam; Liu, Jinsong; Mukherjee, Priyabrata; Reddy, E Premkumar; Song, Yong Sang; Dhanasekaran, Danny N

Rigosertib is a more effective radiosensitizer than cisplatin in concurrent chemoradiation treatment of cervical carcinoma, in vitro and in vivo

在宫颈癌同步放化疗中,体外和体内实验均表明,Rigosertib 比顺铂更有效,是一种更有效的放射增敏剂,无论在体外还是体内。

Agoni, Lorenzo; Basu, Indranil; Gupta, Seema; Alfieri, Alan; Gambino, Angela; Goldberg, Gary L; Reddy, E Premkumar; Guha, Chandan

Preclinical pharmacological evaluation of a novel multiple kinase inhibitor, ON123300, in brain tumor models

在脑肿瘤模型中对新型多激酶抑制剂 ON123300 进行临床前药理学评价

Zhang, Xiaoping; Lv, Hua; Zhou, Qingyu; Elkholi, Rana; Chipuk, Jerry E; Reddy, M V Ramana; Reddy, E Premkumar; Gallo, James M

Myb permits multilineage airway epithelial cell differentiation

Myb 允许气道上皮细胞进行多谱系分化

Pan, Jie-Hong; Adair-Kirk, Tracy L; Patel, Anand C; Huang, Tao; Yozamp, Nicholas S; Xu, Jian; Reddy, E Premkumar; Byers, Derek E; Pierce, Richard A; Holtzman, Michael J; Brody, Steven L