日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss-of-function Gα(s) rare disease variants exert mutation-specific effects on GPCR signaling

功能丧失的Gα(s)罕见疾病变异体对GPCR信号传导产生突变特异性影响

Redfern-Nichols, Theo; O'Brien, Shannon L; Huang, Xianglin; Medel-Lacruz, Brian; Calebiro, Davide; Selent, Jana; Ladds, Graham; Marti-Solano, Maria

Agonist efficacy at the β(2)AR is driven by the faster association rate of the G(s) protein.

β(2)AR 激动剂的效力取决于 G(s) 蛋白结合速率的加快

Harwood Clare R, Sykes David A, Redfern-Nichols Theo, Underwood Owen, Nicholson Colin, Khoshgrudi Armin N, Koers Eline J, Ladds Graham, Briddon Stephen J, Veprintsev Dmitry B

Quantitative approaches for studying G protein-coupled receptor signalling and pharmacology

用于研究G蛋白偶联受体信号传导和药理学的定量方法

Pearce, Abigail; Redfern-Nichols, Theo; Wills, Edward; Rosa, Matthew; Manulak, Iga; Sisk, Claudia; Huang, Xianglin; Atakpa-Adaji, Peace; Prole, David L; Ladds, Graham