38: Presence of tertiary lymphoid structures and exhausted tissue-resident T cells determines clinical response to PD-1 blockade in renal cell carcinoma
38：肾细胞癌中三级淋巴结构和耗竭的组织驻留T细胞的存在决定了PD-1阻断疗法的临床疗效
期刊:Nature
影响因子:48.5
doi:10.1038/s41586-025-09460-7
Scott, Andrew J; Mittal, Anjali; Meghdadi, Baharan; O'Brien, Alexandra; Bailleul, Justine; Sravya, Palavalasa; Achreja, Abhinav; Zhou, Weihua; Xu, Jie; Lin, Angelica; Wilder-Romans, Kari; Liang, Ningning; Kothari, Ayesha U; Korimerla, Navyateja; Edwards, Donna M; Wu, Zhe; Feng, Jiane; Su, Sophia; Zhang, Li; Sajjakulnukit, Peter; Andren, Anthony C; Park, Junyoung O; Ten Hoeve, Johanna; Tarnal, Vijay; Redic, Kimberly A; Qi, Nathan R; Fischer, Joshua L; Yang, Ethan; Regan, Michael S; Stopka, Sylwia A; Baquer, Gerard; Suresh, Krithika; Sarkaria, Jann N; Lawrence, Theodore S; Venneti, Sriram; Agar, Nathalie Y R; Vlashi, Erina; Lyssiotis, Costas A; Al-Holou, Wajd N; Nagrath, Deepak; Wahl, Daniel R; Salgia, Nicholas; Kauffman, Eric; Muhitch, Jason; Burns, Ethan; Kashima, Soki; Rout, Rishabh; Hugaboom, Miya; Ye, Zhaochen; Schindler, Nicholas; Dighe, Anasuya; Sun, Maxine; Lee, Gwo-Shu Mary; Xu, Wenxin (Vincent); Atkins, Michael B; Signoretti, Sabina; McGregor, Bradley A; McKay, Rana; Choueri, Toni; Braun, David; Wirth, Lena; Hugaboom, Miya; Street, Kelly; Ruthen, Neil; Jegede, Opeyemi; Schindler, Nicholas; Shah, Valisha; Zaemes, Jacob; Ahmar, Nourhan El; Matar, Sayed; Savla, Varunika; Choueri, Toni; Denize, Thomas; West, Destiny; McDermott, David; Plimack, Elizabeth; Sosman, Jeffrey A; Haas, Naomi B; Hurwitz, Michael; Hammers, Hans J; Stein, Mark N; Alter, Robert; Bilen, Mehmet; Signoretti, Sabina; Atkins, Michael B; Wu, Catherine; Braun, David
肿瘤
T细胞
肿瘤免疫
肾癌
T细胞
细胞生物学
PD-1
免疫/内分泌
