Reeby相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

TNF-Î±/NF-ÎºB mediated upregulation of Dectin-1 in hyperglycemic obesity: implications for metabolic inflammation and diabetes.

TNF-α/NF-αB介导的高血糖肥胖中Dectin-1的上调：对代谢炎症和糖尿病的影响

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/s12967-025-06303-x

Al Madhoun Ashraf, Haddad Dania, Kochumon Shihab, Thomas Reeby, Miranda Lavina, George Preethi, Abu-Khalaf Nermeen, Al-Mulla Fahd, Ahmad Rasheed

发表日期：2025

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Neutral Sphingomyelinase 2 Inhibition Limits Hepatic Steatosis and Inflammation

中性鞘磷脂酶 2 抑制剂可限制肝脏脂肪变性和炎症

影响因子:5.1

doi:10.3390/cells13050463

Fatema Al-Rashed, Hossein Arefanian, Ashraf Al Madhoun, Fatemah Bahman, Sardar Sindhu, Halemah AlSaeed, Texy Jacob, Reeby Thomas, Areej Al-Roub, Fawaz Alzaid, M D Zubbair Malik, Rasheeba Nizam, Thangavel Alphonse Thanaraj, Fahd Al-Mulla, Yusuf A Hannun, Rasheed Ahmad

发表日期：2024

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Gut Dysbiosis Shaped by Cocoa Butter-Based Sucrose-Free HFD Leads to Steatohepatitis, and Insulin Resistance in Mice

以可可脂为基础的无蔗糖高脂饮食导致小鼠肠道菌群失调，进而引发脂肪性肝炎和胰岛素抵抗。

期刊:Nutrients

doi:10.3390/nu16121929

Kochumon, Shihab; Malik, Md Zubbair; Sindhu, Sardar; Arefanian, Hossein; Jacob, Texy; Bahman, Fatemah; Nizam, Rasheeba; Hasan, Amal; Thomas, Reeby; Al-Rashed, Fatema; Shenouda, Steve; Wilson, Ajit; Albeloushi, Shaima; Almansour, Nourah; Alhamar, Ghadeer; Al Madhoun, Ashraf; Alzaid, Fawaz; Thanaraj, Thangavel Alphonse; Koistinen, Heikki A; Tuomilehto, Jaakko; Al-Mulla, Fahd; Ahmad, Rasheed

免疫/内分泌

发表日期：2024

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Soybean oil-based HFD induces gut dysbiosis that leads to steatosis, hepatic inflammation and insulin resistance in mice

以大豆油为基础的高脂饮食会诱发小鼠肠道菌群失调，从而导致脂肪变性、肝脏炎症和胰岛素抵抗

期刊:Frontiers in Microbiology

doi:10.3389/fmicb.2024.1407258

Texy Jacob #, Sardar Sindhu #, Amal Hasan #, Md Zubbair Malik #, Hossein Arefanian, Fatema Al-Rashed, Rasheeba Nizam, Shihab Kochumon, Reeby Thomas, Fatemah Bahman, Steve Shenouda, Ajit Wilson, Nadeem Akther, Areej Al-Roub, Nermeen Abukhalaf, Shaima Albeloushi, Mohamed Abu-Farha, Ashraf Al Madhoun,

发表日期：2024

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Adipose Tissue Caveolin-1 Upregulation in Obesity Involves TNF-α/NF-κB Mediated Signaling

肥胖中的脂肪组织 Caveolin-1 上调涉及 TNF-α/NF-κB 介导的信号传导

影响因子:5.1

doi:10.3390/cells12071019

Ashraf Al Madhoun, Shihab Kochumon, Dania Haddad, Reeby Thomas, Rasheeba Nizam, Lavina Miranda, Sardar Sindhu, Milad S Bitar, Rasheed Ahmad, Fahd Al-Mulla

发表日期：2023

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Endoplasmic Reticulum Stress Promotes the Expression of TNF-α in THP-1 Cells by Mechanisms Involving ROS/CHOP/HIF-1α and MAPK/NF-κB Pathways

内质网应激通过ROS/CHOP/HIF-1α和MAPK/NF-κB通路促进THP-1细胞TNF-α表达

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms242015186

Nadeem Akhter, Ajit Wilson, Hossein Arefanian, Reeby Thomas, Shihab Kochumon, Fatema Al-Rashed, Mohamed Abu-Farha, Ashraf Al-Madhoun, Fahd Al-Mulla, Rasheed Ahmad, Sardar Sindhu

发表日期：2023

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Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b

肝脏IRF3通过直接调节Ppp2r1b促进肥胖中的血糖异常

期刊:Science Translational Medicine

影响因子:14.6

doi:10.1126/scitranslmed.abh3831

Patel, Suraj J; Liu, Nan; Piaker, Sam; Gulko, Anton; Andrade, Maynara L; Heyward, Frankie D; Sermersheim, Tyler; Edinger, Nufar; Srinivasan, Harini; Emont, Margo P; Westcott, Gregory P; Luther, Jay; Chung, Raymond T; Yan, Shuai; Kumari, Manju; Thomas, Reeby; Deleye, Yann; Tchernof, André; White, Phillip J; Baselli, Guido A; Meroni, Marica; De Jesus, Dario F; Ahmad, Rasheed; Kulkarni, Rohit N; Valenti, Luca; Tsai, Linus; Rosen, Evan D

发表日期：2022

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Expression of Steroid Receptor RNA Activator 1 (SRA1) in the Adipose Tissue Is Associated with TLRs and IRFs in Diabesity

脂肪组织中类固醇受体 RNA 激活剂 1 (SRA1) 的表达与糖尿病肥胖症中的 TLR 和 IRF 相关

影响因子:5.1

doi:10.3390/cells11244007

Shihab Kochumon, Hossein Arefanian, Sardar Sindhu, Reeby Thomas, Texy Jacob, Amnah Al-Sayyar, Steve Shenouda, Fatema Al-Rashed, Heikki A Koistinen, Fahd Al-Mulla, Jaakko Tuomilehto, Rasheed Ahmad

发表日期：2022

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Caveolin-1 rs1997623 Single Nucleotide Polymorphism Creates a New Binding Site for the Early B-Cell Factor 1 That Instigates Adipose Tissue CAV1 Protein Overexpression

Caveolin-1 rs1997623 单核苷酸多态性为早期 B 细胞因子 1 创建新的结合位点，从而引发脂肪组织 CAV1 蛋白过度表达

影响因子:5.1

doi:10.3390/cells11233937

Ashraf Al Madhoun, Dania Haddad, Rasheeba Nizam, Lavina Miranda, Shihab Kochumon, Reeby Thomas, Thangavel Alphonse Thanaraj, Rasheed Ahmad, Milad S Bitar, Fahd Al-Mulla

细胞生物学

发表日期：2022

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Increased Adipose Tissue Expression of IL-23 Associates with Inflammatory Markers in People with High LDL Cholesterol

IL-23 脂肪组织表达增加与高 LDL 胆固醇人群的炎症标志物相关

影响因子:5.1

doi:10.3390/cells11193072

Shihab Kochumon, Amal Hasan, Fatema Al-Rashed, Sardar Sindhu, Reeby Thomas, Texy Jacob, Amnah Al-Sayyar, Hossein Arefanian, Ashraf Al Madhoun, Ebaa Al-Ozairi, Fawaz Alzaid, Heikki A Koistinen, Fahd Al-Mulla, Jaakko Tuomilehto, Rasheed Ahmad

发表日期：2022

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