日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The search for CDK4/6 inhibitor biomarkers has been hampered by inappropriate proliferation assays

不适当的增殖检测阻碍了 CDK4/6 抑制剂生物标志物的搜索

Reece Foy, Kah Xin Lew, Adrian T Saurin

CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence

CDK4/6 抑制剂介导的细胞过度生长引发渗透和复制应激,从而促进衰老

Lisa Crozier, Reece Foy, Rozita Adib, Ananya Kar, Jordan A Holt, Aanchal U Pareri, Juan M Valverde, Rene Rivera, William A Weston, Rona Wilson, Clement Regnault, Phil Whitfield, Mihaly Badonyi, Laura G Bennett, Ellen G Vernon, Amelia Gamble, Joseph A Marsh, Christopher J Staples, Adrian T Saurin, Al

Oncogenic signals prime cancer cells for toxic cell overgrowth during a G1 cell cycle arrest

致癌信号在 G1 细胞周期停滞期间引发癌细胞毒性细胞过度生长

Reece Foy, Lisa Crozier, Aanchal U Pareri, Juan Manuel Valverde, Ben Ho Park, Tony Ly, Adrian T Saurin

CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal

CDK4/6 抑制剂诱导复制压力导致长期细胞周期停滞

Lisa Crozier #, Reece Foy #, Brandon L Mouery, Robert H Whitaker, Andrea Corno, Christos Spanos, Tony Ly, Jeanette Gowen Cook, Adrian T Saurin