日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bcl-2 on the brink of breakthroughs in cancer treatment

Bcl-2 即将在癌症治疗领域取得突破

Reed, John C

Finally, An Apoptosis-Targeting Therapeutic for Cancer

最后,一种靶向细胞凋亡的癌症治疗方法问世。

Croce, Carlo M; Reed, John C

Ubc13 haploinsufficiency protects against age-related insulin resistance and high-fat diet-induced obesity

Ubc13单倍体不足可预防与年龄相关的胰岛素抵抗和高脂饮食诱导的肥胖。

Joo, Erina; Fukushima, Toru; Harada, Norio; Reed, John C; Matsuzawa, Shu-Ichi; Inagaki, Nobuya

Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes

利用小分子探针推进生物学理解和治疗药物发现

Schreiber, Stuart L; Kotz, Joanne D; Li, Min; Aubé, Jeffrey; Austin, Christopher P; Reed, John C; Rosen, Hugh; White, E Lucile; Sklar, Larry A; Lindsley, Craig W; Alexander, Benjamin R; Bittker, Joshua A; Clemons, Paul A; de Souza, Andrea; Foley, Michael A; Palmer, Michelle; Shamji, Alykhan F; Wawer, Mathias J; McManus, Owen; Wu, Meng; Zou, Beiyan; Yu, Haibo; Golden, Jennifer E; Schoenen, Frank J; Simeonov, Anton; Jadhav, Ajit; Jackson, Michael R; Pinkerton, Anthony B; Chung, Thomas D Y; Griffin, Patrick R; Cravatt, Benjamin F; Hodder, Peter S; Roush, William R; Roberts, Edward; Chung, Dong-Hoon; Jonsson, Colleen B; Noah, James W; Severson, William E; Ananthan, Subramaniam; Edwards, Bruce; Oprea, Tudor I; Conn, P Jeffrey; Hopkins, Corey R; Wood, Michael R; Stauffer, Shaun R; Emmitte, Kyle A

Enhanced prostate cancer gene transfer and therapy using a novel serotype chimera cancer terminator virus (Ad.5/3-CTV)

利用新型血清型嵌合癌症终结病毒(Ad.5/3-CTV)增强前列腺癌基因转移和治疗

Azab, Belal M; Dash, Rupesh; Das, Swadesh K; Bhutia, Sujit K; Sarkar, Siddik; Shen, Xue-Ning; Quinn, Bridget A; Dent, Paul; Dmitriev, Igor P; Wang, Xiang-Yang; Curiel, David T; Pellecchia, Maurizio; Reed, John C; Sarkar, Devanand; Fisher, Paul B

Ultra-High-Throughput Screening of Natural Product Extracts to Identify Proapoptotic Inhibitors of Bcl-2 Family Proteins

利用超高通量筛选天然产物提取物以鉴定Bcl-2家族蛋白的促凋亡抑制剂

Hassig, Christian A; Zeng, Fu-Yue; Kung, Paul; Kiankarimi, Mehrak; Kim, Sylvia; Diaz, Paul W; Zhai, Dayong; Welsh, Kate; Morshedian, Shana; Su, Ying; O'Keefe, Barry; Newman, David J; Rusman, Yudi; Kaur, Harneet; Salomon, Christine E; Brown, Susan G; Baire, Beeraiah; Michel, Andrew R; Hoye, Thomas R; Francis, Subhashree; Georg, Gunda I; Walters, Michael A; Divlianska, Daniela B; Roth, Gregory P; Wright, Amy E; Reed, John C

A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition

泛BCL2抑制剂使骨髓驻留的人类白血病干细胞对酪氨酸激酶抑制剂敏感

Goff, Daniel J; Court Recart, Angela; Sadarangani, Anil; Chun, Hye-Jung; Barrett, Christian L; Krajewska, Maryla; Leu, Heather; Low-Marchelli, Janine; Ma, Wenxue; Shih, Alice Y; Wei, Jun; Zhai, Dayong; Geron, Ifat; Pu, Minya; Bao, Lei; Chuang, Ryan; Balaian, Larisa; Gotlib, Jason; Minden, Mark; Martinelli, Giovanni; Rusert, Jessica; Dao, Kim-Hien; Shazand, Kamran; Wentworth, Peggy; Smith, Kristen M; Jamieson, Christina A M; Morris, Sheldon R; Messer, Karen; Goldstein, Lawrence S B; Hudson, Thomas J; Marra, Marco; Frazer, Kelly A; Pellecchia, Maurizio; Reed, John C; Jamieson, Catriona H M

Tumour cell survival mechanisms in lethal metastatic prostate cancer differ between bone and soft tissue metastases

致命性转移性前列腺癌中,肿瘤细胞的存活机制在骨转移和软组织转移中有所不同。

Akfirat, Canan; Zhang, Xiaotun; Ventura, Aviva; Berel, Dror; Colangelo, Mary E; Miranti, Cindy K; Krajewska, Maryla; Reed, John C; Higano, Celestia S; True, Lawrence D; Vessella, Robert L; Morrissey, Colm; Knudsen, Beatrice S

Expedient synthesis of highly potent antagonists of inhibitor of apoptosis proteins (IAPs) with unique selectivity for ML-IAP

高效合成对ML-IAP具有独特选择性的高效凋亡抑制蛋白(IAP)拮抗剂

Vamos, Mitchell; Welsh, Kate; Finlay, Darren; Lee, Pooi San; Mace, Peter D; Snipas, Scott J; Gonzalez, Monica L; Ganji, Santhi Reddy; Ardecky, Robert J; Riedl, Stefan J; Salvesen, Guy S; Vuori, Kristiina; Reed, John C; Cosford, Nicholas D P

Systematic analysis and validation of differential gene expression in ovarian serous adenocarcinomas and normal ovary

卵巢浆液性腺癌和正常卵巢中差异基因表达的系统分析和验证

Bauerschlag, Dirk; Bräutigam, Karen; Moll, Roland; Sehouli, Jalid; Mustea, Alexander; Salehin, Darius; Krajewska, Maryla; Reed, John C; Maass, Nicolai; Hampton, Garret M; Meinhold-Heerlein, Ivo