日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Mucosal kinase activity and inflammatory profiles in inflammatory bowel disease, and in relation to tofacitinib response

炎症性肠病中黏膜激酶活性和炎症特征，以及与托法替尼疗效的关系

期刊:Journal of Crohns & Colitis
影响因子:8.7
doi:10.1093/ecco-jcc/jjaf174
Brand, Eelco C; Roosenboom, Britt; Lutter, Lisanne; Malvar Fernandez, Bea; Rangarajan, Savithri; van Koolwijk, Elly; van Gennep, Sara; D'Haens, Geert R; van Lochem, Ellen G; Horjus Talabur Horje, Carmen S; Reedquist, Kris A; van Wijk, Femke; Oldenburg, Bas
炎症/感染
信号转导
炎症
发表日期：2025
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Central Role of Semaphorin 3B in a Serum-Induced Arthritis Model and Reduced Levels in Patients With Rheumatoid Arthritis

血清诱导关节炎模型中信号素3B的核心作用及其在类风湿性关节炎患者体内水平降低

期刊:Arthritis & Rheumatology
影响因子:10.9
doi:10.1002/art.42065
Igea, Ana; Carvalheiro, Tiago; Malvar-Fernández, Beatriz; Martinez-Ramos, Sara; Rafael-Vidal, Carlos; Niemantsverdriet, Ellis; Varadé, Jezabel; Fernández-Carrera, Andrea; Jimenez, Norman; McGarry, Trudy; Rodriguez-Trillo, Angela; Veale, Douglas; Fearon, Ursula; Conde, Carmen; Pego-Reigosa, Jose M; González-Fernández, África; Reedquist, Kris A; Radstake, Timothy R D J; van der Helm-Van Mil, Annette; García, Samuel
信号转导
关节炎
发表日期：2022
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Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes.

组蛋白去乙酰化酶 3 调节类风湿性关节炎成纤维细胞样滑膜细胞的炎症基因表达程序

期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/annrheumdis-2015-209064
Angiolilli Chiara, Kabala Pawel A, Grabiec Aleksander M, Van Baarsen Iris M, Ferguson Bradley S, García Samuel, Malvar Fernandez Beatriz, McKinsey Timothy A, Tak Paul P, Fossati Gianluca, Mascagni Paolo, Baeten Dominique L, Reedquist Kris A
细胞生物学
关节炎
乙酰化
炎症
发表日期：2017
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Insight into the Endocrine System and the Immune System: A Review of the Inflammatory Role of Prolactin in Rheumatoid Arthritis and Psoriatic Arthritis

深入了解内分泌系统和免疫系统：催乳素在类风湿性关节炎和银屑病关节炎炎症作用的综述

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2017.00720
Tang, Man W; Garcia, Samuel; Gerlag, Danielle M; Tak, Paul P; Reedquist, Kris A
炎症
炎症/感染
银屑病
关节炎
免疫/内分泌
发表日期：2017
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Endoplasmic reticulum stress cooperates with Toll-like receptor ligation in driving activation of rheumatoid arthritis fibroblast-like synoviocytes

内质网应激与 Toll 样受体配体结合协同作用，驱动类风湿性关节炎成纤维细胞样滑膜细胞的活化。

期刊:Arthritis Research & Therapy
影响因子:4.6
doi:10.1186/s13075-017-1386-x
Kabala, Pawel A; Angiolilli, Chiara; Yeremenko, Nataliya; Grabiec, Aleksander M; Giovannone, Barbara; Pots, Desiree; Radstake, Timothy R; Baeten, Dominique; Reedquist, Kris A
成纤维细胞
细胞生物学
信号转导
内质网应激
关节炎
发表日期：2017
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Inflammatory cytokines epigenetically regulate rheumatoid arthritis fibroblast-like synoviocyte activation by suppressing HDAC5 expression

炎症细胞因子通过抑制HDAC5表达，以表观遗传学方式调控类风湿性关节炎成纤维细胞样滑膜细胞的活化。

期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/annrheumdis-2014-205635
Angiolilli, Chiara; Grabiec, Aleksander M; Ferguson, Bradley S; Ospelt, Caroline; Malvar Fernandez, Beatriz; van Es, Inge E; van Baarsen, Lisa G M; Gay, Steffen; McKinsey, Timothy A; Tak, Paul P; Baeten, Dominique L; Reedquist, Kris A
成纤维细胞
炎症
表观遗传
细胞生物学
炎症/感染
信号转导
HDAC5
关节炎
免疫/内分泌
发表日期：2016
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Colony-stimulating factor (CSF) 1 receptor blockade reduces inflammation in human and murine models of rheumatoid arthritis

集落刺激因子 (CSF) 1 受体阻断可减轻人类和鼠类风湿性关节炎模型中的炎症

期刊:Arthritis Research & Therapy
影响因子:4.6
doi:10.1186/s13075-016-0973-6
Garcia, Samuel; Hartkamp, Linda M; Malvar-Fernandez, B; van Es, Inge E; Lin, Haishan; Wong, Justin; Long, Li; Zanghi, James A; Rankin, Andrew L; Masteller, Emma L; Wong, Brian R; Radstake, Timothy R D J; Tak, Paul P; Reedquist, Kris A
炎症/感染
信号转导
关节炎
炎症
发表日期：2016
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The prolactin receptor is expressed in rheumatoid arthritis and psoriatic arthritis synovial tissue and contributes to macrophage activation

催乳素受体在类风湿性关节炎和银屑病关节炎的滑膜组织中表达，并促进巨噬细胞活化。

期刊:Rheumatology
影响因子:4.4
doi:10.1093/rheumatology/kew316
Tang, Man Wai; Reedquist, Kris A; Garcia, Samuel; Fernandez, Bea Malvar; Codullo, Veronica; Vieira-Sousa, Elsa; Goffin, Vincent; Reuwer, Anne Q; Twickler, Marcel T; Gerlag, Daniëlle M; Tak, Paul-Peter
信号转导
细胞生物学
免疫/内分泌
银屑病
巨噬细胞
关节炎
巨噬细胞
发表日期：2016
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FMS-related tyrosine kinase 3 ligand (Flt3L)/CD135 axis in rheumatoid arthritis

类风湿性关节炎中的FMS相关酪氨酸激酶3配体（Flt3L）/CD135轴

期刊:Arthritis Research & Therapy
影响因子:4.6
doi:10.1186/ar4403
Ramos, Maria I; Perez, Samuel Garcia; Aarrass, Saida; Helder, Boy; Broekstra, Pleun; Gerlag, Daan M; Reedquist, Kris A; Tak, Paul Peter; Lebre, Maria C
信号转导
多发性硬化症
关节炎
CD13
CD135
发表日期：2013
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Selective involvement of ERK and JNK mitogen-activated protein kinases in early rheumatoid arthritis (1987 ACR criteria compared to 2010 ACR/EULAR criteria): a prospective study aimed at identification of diagnostic and prognostic biomarkers as well as therapeutic targets

ERK 和 JNK 丝裂原活化蛋白激酶在早期类风湿关节炎中的选择性参与（1987 年 ACR 标准与 2010 年 ACR/EULAR 标准比较）：一项旨在识别诊断和预后生物标志物以及治疗靶点的前瞻性研究

期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/ard.2010.143529
de Launay, Daphne; van de Sande, Marleen G H; de Hair, Maria J H; Grabiec, Aleksander M; van de Sande, Gijs P M; Lehmann, K Aad; Wijbrandts, Carla A; van Baarsen, Lisa G M; Gerlag, Danielle M; Tak, Paul P; Reedquist, Kris A
信号转导
关节炎
JNK
MAPK/ERK
发表日期：2012
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