日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dual IL-6 and CTLA-4 blockade regresses pancreatic tumors in a T cell- and CXCR3-dependent manner

IL-6 和 CTLA-4 双重阻断以 T 细胞和 CXCR3 依赖的方式使胰腺肿瘤消退。

Michael Brandon Ware ,Maggie Phillips ,Christopher McQuinn ,Mohammad Y Zaidi ,Hannah M Knochelmann ,Emily Greene ,Brian Robinson ,Cameron J Herting ,Thomas A Mace ,Zhengjia Chen ,Chao Zhang ,Matthew R Farren ,Amanda N Ruggieri ,Jacob S Bowers ,Reena Shakya ,Alton B Farris ,Gregory Young ,William E Carson 3rd ,Bassel El-Rayes ,Chrystal M Paulos ,Gregory B Lesinski

EMT alterations in the solute carrier landscape uncover SLC22A10/A15 imposed vulnerabilities in pancreatic cancer

溶质载体景观中的 EMT 改变揭示了 SLC22A10/A15 在胰腺癌中造成的脆弱性

Debasis Nayak, Brenna Weadick, Avinash K Persaud, Radhika Raj, Reena Shakya, Junan Li, Moray J Campbell, Rajgopal Govindarajan

The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer

小 G 蛋白 RalA 促进三阴性乳腺癌的进展和转移

Katie A Thies, Matthew W Cole, Rachel E Schafer, Jonathan M Spehar, Dillon S Richardson, Sarah A Steck, Manjusri Das, Arthur W Lian, Alo Ray, Reena Shakya, Sue E Knoblaugh, Cynthia D Timmers, Michael C Ostrowski, Arnab Chakravarti, Gina M Sizemore, Steven T Sizemore

Ablation of the Brca1-Palb2 Interaction Phenocopies Fanconi Anemia in Mice

Brca1-Palb2 相互作用的消融可复制小鼠范康尼贫血症

Dongju Park, Stephen M Bergin, Dan Jones, Peng Ru, Christopher S Koivisto, Young-Jun Jeon, Gina M Sizemore, Raleigh D Kladney, Ashley Hadjis, Reena Shakya, Thomas Ludwig

CD200 promotes immunosuppression in the pancreatic tumor microenvironment

CD200 促进胰腺肿瘤微环境中的免疫抑制

Fouad Choueiry, Molly Torok, Reena Shakya, Kriti Agrawal, Anna Deems, Brooke Benner, Alice Hinton, Jami Shaffer, Bradley W Blaser, Anne M Noonan, Terence M Williams, Mary Dillhoff, Darwin L Conwell, Phil A Hart, Zobeida Cruz-Monserrate, Xue-Feng Bai, William E Carson 3rd, Thomas A Mace

Intein-mediated cytoplasmic reconstitution of a split toxin enables selective cell ablation in mixed populations and tumor xenografts

内含肽介导的分裂毒素细胞质重建可在混合群体和肿瘤异种移植中进行选择性细胞消融

Vedud Purde, Elena Kudryashova, David B Heisler, Reena Shakya, Dmitri S Kudryashov

Modeling Human Cancer-induced Cachexia

模拟人类癌症引起的恶病质

Erin E Talbert ,Maria C Cuitiño ,Katherine J Ladner ,Priyani V Rajasekerea ,Melissa Siebert ,Reena Shakya ,Gustavo W Leone ,Michael C Ostrowski ,Brian Paleo ,Noah Weisleder ,Peter J Reiser ,Amy Webb ,Cynthia D Timmers ,Daniel S Eiferman ,David C Evans ,Mary E Dillhoff ,Carl R Schmidt ,Denis C Guttridge

Degree of MDM2 Amplification Affects Clinical Outcomes in Dedifferentiated Liposarcoma

MDM2 扩增程度影响去分化脂肪肉瘤的临床结果

Kate Lynn J Bill, Nathan D Seligson, John L Hays, Achal Awasthi, Bryce Demoret, Colin W Stets, Megan C Duggan, Manojkumar Bupathi, Guy N Brock, Sherri Z Millis, Reena Shakya, Cynthia D Timmers, Paul E Wakely Jr, Raphael E Pollock, James L Chen

Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains

家族性胰腺癌的小鼠模型:Palb2、Brca1 和 Brca2 突变小鼠品系癌症的组织病理学、潜伏期和药物敏感性

Dongju Park, Reena Shakya, Christopher Koivisto, Jason R Pitarresi, Matthias Szabolcs, Raleigh Kladney, Ashley Hadjis, Thomas A Mace, Thomas Ludwig

Inhibition of histone deacetylase 2 reduces MDM2 expression and reduces tumor growth in dedifferentiated liposarcoma

抑制组蛋白去乙酰化酶 2 可降低 MDM2 表达并减少去分化脂肪肉瘤中的肿瘤生长

Nathan D Seligson #, Colin W Stets #, Bryce W Demoret, Achal Awasthi, Nicholas Grosenbacher, Reena Shakya, John L Hays, James L Chen