日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Monitoring in real time and far-red imaging of H(2)O(2) dynamics with subcellular resolution

以亚细胞分辨率实时监测和远红外成像H₂O₂动态变化

Lee, Justin Daho; Nguyen, Amanda; Gibbs, Chelsea E; Jin, Zheyu Ruby; Wang, Yuxuan; Moghadasi, Aida; Wait, Sarah J; Choi, Hojun; Evitts, Kira M; Asencio, Anthony; Bremner, Samantha B; Zuniga, Shani; Chavan, Vedant; Pranoto, Inez K A; Williams, C Andrew; Smith, Annette; Moussavi-Harami, Farid; Regnier, Michael; Baker, David; Young, Jessica E; Mack, David L; Nance, Elizabeth; Boyle, Patrick M; Berndt, Andre

Functional interrogation of contextually correct MYH7 variants using CRaTER-flox gene editing and contractility profiling

利用 CRaTER-flox 基因编辑和收缩性分析对上下文正确的 MYH7 变体进行功能性研究

Loiben, Alexander M; Chien, Wei-Ming; McKinstry, Ashley; Ahmed, Dania; Childers, Matthew C; Regnier, Michael; Murry, Charles E; Yang, Kai-Chun

Conformational state of myosin's disordered loop 2 structure mediates actomyosin association during crossbridge formation

肌球蛋白无序环2结构的构象状态介导横桥形成过程中肌动球蛋白的结合

Robeson, Kalen Z; Childers, Matthew Carter; Fruebis, Kieran J; Soriano, Rachelle; Davis, Jennifer; Regnier, Michael

In silico conformational dynamics of the α-actinin-2 actin-binding domain upon phosphorylation

α-辅肌动蛋白-2肌动蛋白结合域磷酸化后的计算机模拟构象动力学

Tigro, Helene; Childers, Matthew C; Regnier, Michael; Solís, Christopher

Spatial relationships between vinculin tension and actin at cell adhesions define cell colony positioning and identity.

细胞粘附处黏着斑蛋白张力与肌动蛋白之间的空间关系决定了细胞群落的定位和特性。

Nagle Abigail, Leung Cherry, Karbassi Elaheh, Young Jessica, Regnier Michael, Davis Jennifer

Phosphoproteomics of Hypertrophic Cardiomyopathy Patient Myocardium and Novel hiPSC-CM Model Reveal Protein Kinase A as a Modulator of Microtubule Repolymerization

肥厚型心肌病患者心肌和新型hiPSC-CM模型的磷酸化蛋白质组学研究揭示蛋白激酶A作为微管重聚合的调节因子

Algül, Sıla; Duursma, Inez; Hesson, Jennifer; Mathieu, Julie; de Goeij-de Haas, Richard; Henneman, Alex A; Piersma, Sander R; Pham, Thang V; Schoonvelde, Stephan A C; Michels, Michelle; Soleilhac, Jean-Marc; Moutin, Marie-Jo; Jimenez, Connie R; Regnier, Michael; Kuster, Diederik W D; van der Velden, Jolanda

Preventing hypocontractility-induced fibroblast expansion alleviates dilated cardiomyopathy

预防低收缩力诱导的成纤维细胞增殖可缓解扩张型心肌病

Bretherton, Ross C; Reichardt, Isabella M; Zabrecky, Kristin A; Nagle, Abigail; Bailey, Logan R J; Bugg, Darrian; Smolgovsky, Sasha; Gifford, Amy L; McMillen, Timothy S; Goldstein, Alex J; Kooiker, Kristina B; Flint, Galina V; Martinson, Amy; Gunaje, Jagdambika; Koser, Franziska; Plaster, Elizabeth; Linke, Wolfgang A; Regnier, Michael; Moussavi-Harami, Farid; Sniadecki, Nathan J; DeForest, Cole A; Davis, Jennifer

Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human β-cardiac myosin allosterically

肥厚型心肌病突变Y115H和E497D通过变构作用破坏人β-心肌肌球蛋白的折叠状态。

Nandwani, Neha; Bhowmik, Debanjan; Glaser, Camille; Childers, Matthew Carter; Goluguri, Rama Reddy; Dawood, Aminah; Regnier, Michael; Houdusse, Anne; Spudich, James A; Ruppel, Kathleen M

Expression of full-length dystrophin reverses muscular dystrophy defects in young and old mdx4cv mice.

全长肌营养不良蛋白的表达可以逆转年轻和年老的 mdx4cv 小鼠的肌肉营养不良缺陷

Tasfaout Hichem, McMillen Timothy S, Reyes Theodore R, Halbert Christine L, Tian Rong, Regnier Michael, Chamberlain Jeffrey S

Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model

猪心室肌和人干细胞衍生心肌细胞模型中β-肌球蛋白R403Q突变导致收缩功能改变的分子机制

Steczina, Sonette; Mohran, Saffie; Childers, Matthew C; McMillen, Timothy S; Naim, Ateeqa; Pilagov, Matvey; Dente, Marica; Kooiker, Kristina B; Mandrycky, Christian; Tawde, Khushi; Hesson, Jennifer; Zhao, Jing; Mathieu, Julie; Pioner, J Manuel; Geeves, Michael A; Ma, Weikang; Moussavi-Harami, Farid; Kad, Neil M; Regnier, Michael