日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Bioisosteric replacement of pyridoxal-5'-phosphate to pyridoxal-5'-tetrazole targeting Bacillus subtilis GabR

吡哆醛-5'-磷酸酯生物等排体置换为吡哆醛-5'-四唑靶向枯草芽孢杆菌GabR

Kaley, Nicholas E; Liveris, Zachary J; Moore, Maxwell; Reidl, Cory T; Wawrzak, Zdzislaw; Becker, Daniel P; Liu, Dali

Cyclobutanone Inhibitors of Diaminopimelate Desuccinylase (DapE) as Potential New Antibiotics

环丁酮类二氨基庚二酸脱琥珀酰酶(DapE)抑制剂作为潜在的新型抗生素

Habeeb Mohammad, Thahani S; Kelley, Emma H; Reidl, Cory T; Konczak, Katherine; Beulke, Megan; Javier, Janielle; Olsen, Kenneth W; Becker, Daniel P

Small molecules targeting different cellular pathologies for the treatment of amyotrophic lateral sclerosis

针对不同细胞病理的小分子药物用于治疗肌萎缩侧索硬化症

Elmansy, Mohamed F; Reidl, Cory T; Rahaman, Mizzanoor; Özdinler, P Hande; Silverman, Richard B

Mapping roles of active site residues in the acceptor site of the PA3944 Gcn5-related N-acetyltransferase enzyme.

绘制 PA3944 Gcn5 相关 N-乙酰转移酶受体位点活性位点残基的作用图谱

Variot Cillian, Capule Daniel, Arolli Xhulio, Baumgartner Jackson, Reidl Cory, Houseman Charles, Ballicora Miguel A, Becker Daniel P, Kuhn Misty L

Improved synthesis and anticancer activity of a potent neuronal nitric oxide synthase inhibitor

改进的强效神经元一氧化氮合酶抑制剂的合成及其抗癌活性

Vasu, Dhananjayan; Reidl, Cory T; Wang, Eric; Yang, Sun; Silverman, Richard B

(S)-4-Amino-5-phenoxypentanoate designed as a potential selective agonist of the bacterial transcription factor GabR

(S)-4-氨基-5-苯氧基戊酸酯被设计为一种潜在的细菌转录因子GabR选择性激动剂。

Catlin, Daniel S; Reidl, Cory T; Trzupek, Thomas R; Silverman, Richard B; Cannon, Brian L; Becker, Daniel P; Liu, Dali

Indoline-6-Sulfonamide Inhibitors of the Bacterial Enzyme DapE

吲哚啉-6-磺酰胺类化合物是细菌酶DapE的抑制剂。

Reidl, Cory T; Heath, Tahirah K; Darwish, Iman; Torrez, Rachel M; Moore, Maxwell; Gild, Elliot; Nocek, Boguslaw P; Starus, Anna; Holz, Richard C; Becker, Daniel P

Structural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism

DapE酶底物结合引发重大构象变化的结构证据:对催化机制的影响

Nocek, Boguslaw; Reidl, Cory; Starus, Anna; Heath, Tahirah; Bienvenue, David; Osipiuk, Jerzy; Jedrzejczak, Robert; Joachimiak, Andrzej; Becker, Daniel P; Holz, Richard C

Practical spectrophotometric assay for the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase, a potential antibiotic target

一种用于检测dapE编码的N-琥珀酰-L,L-二氨基庚二酸脱琥珀酰酶(一种潜在的抗生素靶点)的实用分光光度法测定方法

Heath, Tahirah K; Lutz, Marlon R Jr; Reidl, Cory T; Guzman, Estefany R; Herbert, Claire A; Nocek, Boguslaw P; Holz, Richard C; Olsen, Kenneth W; Ballicora, Miguel A; Becker, Daniel P

Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases

生成酶和自由基介导的双底物作为研究Gcn5相关N-乙酰转移酶的工具

Reidl, Cory; Majorek, Karolina A; Dang, Joseph; Tran, David; Jew, Kristen; Law, Melissa; Payne, Yasmine; Minor, Wladek; Becker, Daniel P; Kuhn, Misty L