日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Model-Informed Deep Q-Networks to Guide Infliximab Dosing in Pediatric Crohn's Disease

基于模型的深度Q网络指导儿童克罗恩病英夫利昔单抗给药

Irie, Kei; Minar, Phillip; Reifenberg, Jack; Boyle, Brendan M; Noe, Joshua D; Hyams, Jeffrey S; Mizuno, Tomoyuki

Impact of keto leucine and isoleucine on CHO cell central carbon metabolism and performance in fed-batch and steady-state perfusion

酮亮氨酸和异亮氨酸对CHO细胞中心碳代谢及补料分批和稳态灌注培养性能的影响

Reifenberg, Philipp; Benjamin, Daniel; Le Mignon, Maxime; Zimmer, Aline

Machine Learning Modeling for Predicting Infliximab Pharmacokinetics in Pediatric and Young Adult Patients With Crohn Disease: Leveraging Ensemble Modeling With Synthetic and Real-World Data

利用机器学习模型预测英夫利昔单抗在克罗恩病患儿及青少年患者中的药代动力学:结合合成数据和真实世界数据的集成建模

Irie, Kei; Minar, Phillip; Reifenberg, Jack; Boyle, Brendan M; Noe, Joshua D; Hyams, Jeffrey S; Mizuno, Tomoyuki

Hybrid Population Pharmacokinetic-Machine Learning Modeling to Predict Infliximab Pharmacokinetics in Pediatric and Young Adult Patients with Crohn's Disease

采用混合群体药代动力学-机器学习模型预测克罗恩病患儿及青少年患者的英夫利昔单抗药代动力学

Irie, Kei; Minar, Phillip; Reifenberg, Jack; Boyle, Brendan M; Noe, Joshua D; Hyams, Jeffrey S; Mizuno, Tomoyuki

Replacement of Isoleucine and Leucine by their Keto Acids leads to increased formation of α-Hydroxy Acids in Chinese Hamster Ovary cells

用异亮氨酸和亮氨酸的酮酸替代它们会导致中国仓鼠卵巢细胞中α-羟基酸的生成增加。

Reifenberg, Philipp; Rosenberger, Lara; Mignon, Maxime Le; Zimmer, Aline

Hybrid Population PK-Machine Learning Modeling to Predict Infliximab Pharmacokinetics in Pediatric and Young Adult Patients with Crohn's Disease

采用混合群体药代动力学-机器学习模型预测克罗恩病患儿及青少年患者的英夫利昔单抗药代动力学

Irie, Kei; Minar, Phillip; Reifenberg, Jack; Boyle, Brendan M; Noe, Joshua D; Hyams, Jeffrey S; Mizuno, Tomoyuki

Model-informed Deep Q-Networks to Guide Infliximab Dosing in Pediatric Crohn's Disease

基于模型的深度Q网络指导儿童克罗恩病英夫利昔单抗给药

Irie, Kei; Minar, Phillip; Reifenberg, Jack; Boyle, Brendan M; Noe, Joshua D; Hyams, S Jeffrey; Mizuno, Tomoyuki

Branched-chain amino acids: physico-chemical properties, industrial synthesis and role in signaling, metabolism and energy production

支链氨基酸:理化性质、工业合成及其在信号传导、代谢和能量产生中的作用

Reifenberg, Philipp; Zimmer, Aline

Deletion of adipocyte NOS3 potentiates high-fat diet-induced hypertension and vascular remodelling via chemerin

脂肪细胞 NOS3 的缺失会通过趋化因子增强高脂饮食引起的高血压和血管重塑

Andy W C Man, Yawen Zhou, Gisela Reifenberg, Alica Camp, Thomas Münzel, Andreas Daiber, Ning Xia, Huige Li

Lung function and secondhand smoke exposure among children with cystic fibrosis: A Bayesian meta-analysis

囊性纤维化患儿肺功能与二手烟暴露:贝叶斯荟萃分析

Reifenberg, Jack; Gecili, Emrah; Pestian, Teresa; Andrinopoulou, Eleni-Rosalina; Ryan, Patrick H; Brokamp, Cole; Collaco, Joseph M; Szczesniak, Rhonda D