日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Metabolite mimicry identifies butyrate analogs with select protective functions in the intestinal mucosa.

代谢物模拟鉴定出对肠粘膜具有特定保护功能的丁酸类似物。

Ornelas Alfredo, Countess Jacob A, Kim Ji Yeon, Cohen Rachel H, Gomez Brittany D, Roer Rebecca L, Minhajuddin Faiz, Yenugudhati Vijaya Sai Kiranmayee, Zhou Liheng, Dunn Julia L M, Chandler Caleb, Reigan Philip, Cartwright Ian M, Hall Caroline H T, Bhagavatula Geetha, Onyiah Joseph C, Dowdell Alexander S, Colgan Sean P

Chromobox2 inhibition: a novel activity of alisertib, an aurora A kinase inhibitor.

Chromobox2 抑制:alisertib(一种极光 A 激酶抑制剂)的新活性。

Yamamoto Tomomi M, Iwanaga Ritsuko, Woodruff Elizabeth R, Elder Alan M, Petkov Alexander, Nurmemmedov Elmar, Eisenmesser Elan, Reigan Philip, Bitler Benjamin G, Brubaker Lindsay W

The structural requirements of 3,5-substituted oxindoles that determine selective AMPK or GSK3β inhibition

决定选择性抑制AMPK或GSK3β的3,5-取代吲哚酮的结构要求

Strang, Juliet E; Astridge, Daniel D; Chandler, Caleb; Nguyen, Vu T; Reigan, Philip

Small Molecule Modulators of AMP-Activated Protein Kinase (AMPK) Activity and Their Potential in Cancer Therapy

AMP活化蛋白激酶(AMPK)活性的小分子调节剂及其在癌症治疗中的应用潜力

Strang, Juliet E; Astridge, Daniel D; Nguyen, Vu T; Reigan, Philip

RiSKs in Computational Modeling of Isoform-Selective RSK Inhibitors

同工型选择性RSK抑制剂计算建模中的风险

Nguyen, Vu T; Chandler, Caleb; Strang, Juliet E; Astridge, Daniel D; Reigan, Philip

Focal adhesion kinase promotes ribosome biogenesis to drive advanced thyroid cancer cell growth and survival.

黏着斑激酶促进核糖体生物合成,从而驱动晚期甲状腺癌细胞的生长和存活

Kellett Meghan D, Sharma Vibha, Sherlock Madeline E, Pugazhenthi Umarani, Rose Madison M, Joshi Molishree U, Dzieciatkowska Monika, Nguyen Vu, Reigan Philip, Hansen Kirk C, Kieft Jeffrey S, Schweppe Rebecca E

The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function.

贾第鞭毛虫核糖体结构揭示了几个生物途径的差异以及吐根碱的功能模式

Eiler Daniel R, Wimberly Brian T, Bilodeau Danielle Y, Taliaferro J Matthew, Reigan Philip, Rissland Olivia S, Kieft Jeffrey S

Neuroprotective efficacy of the glucocorticoid receptor modulator PT150 in the rotenone mouse model of Parkinson's disease

糖皮质激素受体调节剂 PT150 对鱼藤酮小鼠帕金森病模型的神经保护作用

Amanda S Latham, Savannah M Rocha, Casey P McDermott, Philip Reigan, Richard A Slayden, Ronald B Tjalkens

BRAFV600 and ErbB inhibitors directly activate GCN2 in an off-target manner to limit cancer cell proliferation

BRAFV600 和 ErbB 抑制剂以脱靶方式直接激活 GCN2,从而限制癌细胞增殖

C Ryland Ill, Nasreen C Marikar, Vu Nguyen, Varuna Nangia, Alicia M Darnell, Matthew G Vander Heiden, Philip Reigan, Sabrina L Spencer

Evolutionary degeneration of septins into pseudoGTPases: impacts on a hetero-oligomeric assembly interface

隔蛋白进化退化为假GTP酶:对异源寡聚体组装界面的影响

Hussain, Alya; Nguyen, Vu T; Reigan, Philip; McMurray, Michael