Direct glucosone-based synthesis and HILIC-ESI-MS/MS characterization of N-terminal fructosylated valine and valylhistidine for validation of enzymatic HbA1c assays in the diagnosis of diabetes mellitus

直接基于葡萄糖醛酸的合成和 HILIC-ESI-MS/MS 表征 N 端果糖基化缬氨酸和缬氨酰组氨酸，以验证酶促 HbA1c 检测在糖尿病诊断中的作用