A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models
一种能够在体外模拟药代动力学 (PK) 特征的微流控系统，可提高临床前模型中体内疗效的预测准确性。
期刊:PLoS Biology
影响因子:7.2
doi:10.1371/journal.pbio.3001624
Singh, Dharaminder; Deosarkar, Sudhir P; Cadogan, Elaine; Flemington, Vikki; Bray, Alysha; Zhang, Jingwen; Reiserer, Ronald S; Schaffer, David K; Gerken, Gregory B; Britt, Clayton M; Werner, Erik M; Gibbons, Francis D; Kostrzewski, Tomasz; Chambers, Christopher E; Davies, Emma J; Montoya, Antonio Ramos; Fok, Jacqueline H L; Hughes, David; Fabre, Kristin; Wagoner, Matthew P; Wikswo, John P; Scott, Clay W
