日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Troriluzole attenuates opioid intake, reinforcing efficacy, seeking behaviours, physical dependence and antinociceptive tolerance in rats

Troriluzole可减轻大鼠的阿片类药物摄入量、强化药效、寻求行为、身体依赖性和镇痛耐受性。

Galaj, Ewa; Inan, Saadet; Bi, Guo-Hua; Wiah, Sonita; Adamson, George; Reitz, Allen B; Xi, Zheng-Xiong; Rawls, Scott M

Inhibitors of the Bacterioferritin Ferredoxin Complex Dysregulate Iron Homeostasis and Kill Acinetobacter baumannii and Biofilm-Embedded Pseudomonas aeruginosa Cells

细菌铁蛋白铁氧还蛋白复合物抑制剂会扰乱铁稳态并杀死鲍曼不动杆菌和生物膜包裹的铜绿假单胞菌细胞

Behm, Alexanndra M; Yao, Huili; Eze, Emmanuel C; Alli, Suliat A; Baugh, Simon D P; Ametsetor, Ebenezer; Powell, Kendall M; Battaile, Kevin P; Seibold, Steve; Lovell, Scott; Bunce, Richard A; Reitz, Allen B; Rivera, Mario

DART.2: bidirectional synaptic pharmacology with thousandfold cellular specificity.

DART.2:具有千倍细胞特异性的双向突触药理学

Shields Brenda C, Yan Haidun, Lim Shaun S X, Burwell Sasha C V, Cammarata Celine M, Fleming Elizabeth A, Yousefzadeh S Aryana, Goldenshtein Victoria Z, Kahuno Elizabeth W, Vagadia Purav P, Loughran Marie H, Zhiquan Lei, McDonnell Mark E, Scalabrino Miranda L, Thapa Mishek, Hawley Tammy M, Field Greg D, Hull Court, Schiltz Gary E, Glickfeld Lindsey L, Reitz Allen B, Tadross Michael R

PROTAC-mediated degradation of HIV-1 Nef efficiently restores cell-surface CD4 and MHC-I expression and blocks HIV-1 replication.

PROTAC介导的HIV-1 Nef降解可有效恢复细胞表面CD4和MHC-I的表达,并阻断HIV-1的复制

Emert-Sedlak Lori A, Tice Colin M, Shi Haibin, Alvarado John J, Shu Sherry T, Reitz Allen B, Smithgall Thomas E

A small molecule that targets the processivity factor of molluscum contagiosum virus has therapeutic potential

一种靶向传染性软疣病毒加工因子的小分子具有治疗潜力。

Guan, Hancheng; Nuth, Manunya; Isaacs, Stuart N; Xiao, Yuhong; Scott, Richard W; Parker, Michael H; Strobel, Eric D; Kulp, John L 3rd; Bailey, Thomas R; Reitz, Allen B; Ricciardi, Robert P

Antiretroviral Drug Discovery Targeting the HIV-1 Nef Virulence Factor

针对HIV-1 Nef毒力因子的抗逆转录病毒药物研发

Emert-Sedlak, Lori A; Shi, Haibin; Tice, Colin M; Chen, Li; Alvarado, John J; Shu, Sherry T; Du, Shoucheng; Thomas, Catherine E; Wrobel, Jay E; Reitz, Allen B; Smithgall, Thomas E

Herpes Simplex Virus-1 infection in human primary corneal epithelial cells is blocked by a stapled peptide that targets processive DNA synthesis

单纯疱疹病毒1型感染人原代角膜上皮细胞可通过靶向DNA合成途径的肽链阻断。

Guan, Hancheng; Nuth, Manunya; Lee, Vivian; Lin, Chenyan; Mitchell, Claire H; Lu, Wennan; Scott, Richard W; Parker, Michael H; Kulp, John L 3rd; Reitz, Allen B; Ricciardi, Robert P

Compound FC-10696 Inhibits Egress of Marburg Virus

化合物FC-10696抑制马尔堡病毒的释放

Han, Ziying; Ye, Hong; Liang, Jingjing; Shepley-McTaggart, Ariel; Wrobel, Jay E; Reitz, Allen B; Whigham, Alison; Kavelish, Katrina N; Saporito, Michael S; Freedman, Bruce D; Shtanko, Olena; Harty, Ronald N

Synthesis and evaluation of potent novel inhibitors of human sulfide:quinone oxidoreductase

合成和评价新型高效人硫化物:醌氧化还原酶抑制剂

Baugh, Simon D P; Jackson, Michael R; Rashad, Adel Ahmed; Reitz, Allen B; Lam, Patrick Y S; Jorns, Marilyn Schuman

Cypin: A novel target for traumatic brain injury

Cypin:创伤性脑损伤的新靶点

Swiatkowski, Przemyslaw; Sewell, Emily; Sweet, Eric S; Dickson, Samantha; Swanson, Rachel A; McEwan, Sara A; Cuccolo, Nicholas; McDonnell, Mark E; Patel, Mihir V; Varghese, Nevin; Morrison, Barclay; Reitz, Allen B; Meaney, David F; Firestein, Bonnie L