日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Therapeutic potential of allosteric HECT E3 ligase inhibition.

变构 HECT E3 连接酶抑制的治疗潜力

Rothman Alexander M K, Florentin Amir, Zink Florence, Quigley Catherine, Bonneau Olivier, Hemmig Rene, Hachey Amanda, Rejtar Tomas, Thaker Maulik, Jain Rishi, Huang Shih-Min, Sutton Daniel, Roger Jan, Zhang Ji-Hu, Weiler Sven, Cotesta Simona, Ottl Johannes, Srivastava Salil, Kordonsky Alina, Avishid Reut, Yariv Elon, Rathi Ritu, Khvalevsky Oshrit, Troxler Thomas, Binmahfooz Sarah K, Kleifeld Oded, Morrell Nicholas W, Humbert Marc, Thomas Matthew J, Jarai Gabor, Beckwith Rohan E J, Cobb Jennifer S, Smith Nichola, Ostermann Nils, Tallarico John, Shaw Duncan, Guth-Gundel Sabine, Prag Gali, Rowlands David J

Complement factor B is critical for sub-RPE deposit accumulation in a model of Doyne honeycomb retinal dystrophy with features of age-related macular degeneration

在具有年龄相关性黄斑变性的 Doyne 蜂窝状视网膜营养不良症模型中,补体因子 B 对 RPE 下沉积物的积累至关重要

Maura A Crowley, Donita L Garland, Holger Sellner, Angela Banks, Lin Fan, Tomas Rejtar, Natasha Buchanan, Omar Delgado, Yong Yao Xu, Sandra Jose, Christopher M Adams, Muneto Mogi, Karen Wang, Chad E Bigelow, Stephen Poor, Karen Anderson, Bruce D Jaffee, Ganesh Prasanna, Cynthia Grosskreutz, Rosario

A CRISPR Screen Reveals Resistance Mechanisms to CD3-Bispecific Antibody Therapy

CRISPR筛选揭示了CD3双特异性抗体疗法的耐药机制

Si-Qi Liu ,Alyssa Grantham ,Casey Landry ,Brian Granda ,Rajiv Chopra ,Srinivas Chakravarthy ,Sabine Deutsch ,Markus Vogel ,Katie Russo ,Katherine Seiss ,William R Tschantz ,Tomas Rejtar ,David A Ruddy ,Tiancen Hu ,Kimberly Aardalen ,Joel P Wagner ,Glenn Dranoff ,Joseph A D'Alessio

Quantitative Proteomics of the Cancer Cell Line Encyclopedia

癌症细胞系百科全书的定量蛋白质组学

Nusinow, David P; Szpyt, John; Ghandi, Mahmoud; Rose, Christopher M; McDonald, E Robert 3rd; Kalocsay, Marian; Jané-Valbuena, Judit; Gelfand, Ellen; Schweppe, Devin K; Jedrychowski, Mark; Golji, Javad; Porter, Dale A; Rejtar, Tomas; Wang, Y Karen; Kryukov, Gregory V; Stegmeier, Frank; Erickson, Brian K; Garraway, Levi A; Sellers, William R; Gygi, Steven P

Development of secondary mutations in wild-type and mutant EZH2 alleles cooperates to confer resistance to EZH2 inhibitors

野生型和突变型 EZH2 等位基因的二次突变共同导致对 EZH2 抑制剂的耐药性

V Gibaja, F Shen, J Harari, J Korn, D Ruddy, V Saenz-Vash, H Zhai, T Rejtar, C G Paris, Z Yu, M Lira, D King, W Qi, N Keen, A Q Hassan, H M Chan

Human folliculin delays cell cycle progression through late S and G2/M-phases: effect of phosphorylation and tumor associated mutations

人类卵泡素延缓细胞周期进展至晚期 S 期和 G2/M 期:磷酸化和肿瘤相关突变的影响

Laura A Laviolette, Jonas Wilson, Julia Koller, Christopher Neil, Peter Hulick, Tomas Rejtar, Barry Karger, Bin Tean Teh, Othon Iliopoulos

Integrated proteomic, transcriptomic, and biological network analysis of breast carcinoma reveals molecular features of tumorigenesis and clinical relapse

整合蛋白质组学、转录组学和生物网络分析揭示乳腺癌肿瘤发生和临床复发的分子特征

Imielinski, Marcin; Cha, Sangwon; Rejtar, Tomas; Richardson, Elizabeth A; Karger, Barry L; Sgroi, Dennis C

Ultrasensitive characterization of site-specific glycosylation of affinity-purified haptoglobin from lung cancer patient plasma using 10 μm i.d. porous layer open tubular liquid chromatography-linear ion trap collision-induced dissociation/electron transfer dissociation mass spectrometry

使用 10 μm id 多孔层开管液相色谱-线性离子阱碰撞诱导解离/电子转移解离质谱对来自肺癌患者血浆的亲和纯化结合珠蛋白的位点特异性糖基化进行超灵敏表征

Dongdong Wang, Marina Hincapie, Tomas Rejtar, Barry L Karger

Microproteomic analysis of 10,000 laser captured microdissected breast tumor cells using short-range sodium dodecyl sulfate-polyacrylamide gel electrophoresis and porous layer open tubular liquid chromatography tandem mass spectrometry

使用短程十二烷基硫酸钠-聚丙烯酰胺凝胶电泳和多孔层开管液相色谱串联质谱法对 10,000 个激光捕获微切割乳腺肿瘤细胞进行微蛋白质组学分析

Dipak Thakur, Tomas Rejtar, Dongdong Wang, Jonathan Bones, Sangwon Cha, Buffie Clodfelder-Miller, Elizabeth Richardson, Shemeica Binns, Sonika Dahiya, Dennis Sgroi, Barry L Karger

Histone deacetylase activity is necessary for left-right patterning during vertebrate development

组蛋白去乙酰化酶活性是脊椎动物发育过程中左右模式形成的必要条件

Katia Carneiro, Claudia Donnet, Tomas Rejtar, Barry L Karger, Gustavo A Barisone, Elva Díaz, Sandhya Kortagere, Joan M Lemire, Michael Levin