日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cutting Edge: Protection by Antiviral Memory CD8 T Cells Requires Rapidly Produced Antigen in Large Amounts

前沿研究:抗病毒记忆CD8 T细胞的保护作用需要快速产生大量抗原

Remakus, Sanda; Ma, Xueying; Tang, Lingjuan; Xu, Ren-Huan; Knudson, Cory; Melo-Silva, Carolina R; Rubio, Daniel; Kuo, Yin-Ming; Andrews, Andrew; Sigal, Luis J

Sequential Activation of Two Pathogen-Sensing Pathways Required for Type I Interferon Expression and Resistance to an Acute DNA Virus Infection

两种病原体感知通路的顺序激活是I型干扰素表达和抵抗急性DNA病毒感染所必需的

Xu, Ren-Huan; Wong, Eric B; Rubio, Daniel; Roscoe, Felicia; Ma, Xueying; Nair, Savita; Remakus, Sanda; Schwendener, Reto; John, Shinu; Shlomchik, Mark; Sigal, Luis J

CD4+ T cell help is dispensable for protective CD8+ T cell memory against mousepox virus following vaccinia virus immunization

接种牛痘病毒后,CD4+ T 细胞的辅助对于 CD8+ T 细胞对鼠痘病毒的保护性记忆并非必需。

Fang, Min; Remakus, Sanda; Roscoe, Felicia; Ma, Xueying; Sigal, Luis J

Memory CD8⁺ T cells can outsource IFN-γ production but not cytolytic killing for antiviral protection

记忆性CD8⁺ T细胞可以外包IFN-γ的产生,但不能外包细胞溶解杀伤作用以提供抗病毒保护。

Remakus, Sanda; Rubio, Daniel; Lev, Avital; Ma, Xueying; Fang, Min; Xu, Ren-Huan; Sigal, Luis J

Crosstalk between the type 1 interferon and nuclear factor kappa B pathways confers resistance to a lethal virus infection

I型干扰素和核因子κB通路之间的相互作用赋予机体对致命病毒感染的抵抗力。

Rubio, Daniel; Xu, Ren-Huan; Remakus, Sanda; Krouse, Tracy E; Truckenmiller, Mary Ellen; Thapa, Roshan J; Balachandran, Siddharth; Alcamí, Antonio; Norbury, Christopher C; Sigal, Luis J

Memory CD8+ T cells specific for a single immunodominant or subdominant determinant induced by peptide-dendritic cell immunization protect from an acute lethal viral disease

肽-树突状细胞免疫诱导产生的针对单一免疫优势或亚优势决定簇的记忆性CD8+ T细胞可预防急性致命性病毒疾病。

Remakus, Sanda; Rubio, Daniel; Ma, Xueying; Sette, Alessandro; Sigal, Luis J

Direct presentation is sufficient for an efficient anti-viral CD8+ T cell response

直接呈递足以诱导有效的抗病毒CD8+ T细胞反应。

Xu, Ren-Huan; Remakus, Sanda; Ma, Xueying; Roscoe, Felicia; Sigal, Luis J