日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Efficacy Evaluation of an Intradermally Delivered Enterotoxigenic Escherichia coli CF Antigen I Fimbrial Tip Adhesin Vaccine Coadministered with Heat-Labile Enterotoxin with LT(R192G) against Experimental Challenge with Enterotoxigenic E. coli H10407 in Healthy Adult Volunteers

在健康成年志愿者中对皮内注射产毒大肠杆菌 CF 抗原 I 菌毛尖端粘附素疫苗与热不稳定肠毒素 LT(R192G) 联合给药对产毒大肠杆菌 H10407 实验性攻击的疗效进行评估

Ramiro L Gutiérrez, Chad K Porter, Clayton Harro, Kawsar Talaat, Mark S Riddle, Barbara DeNearing, Jessica Brubaker, Milton Maciel Jr, Renee M Laird, Steven Poole, Subra Chakraborty, Nicole Maier, David A Sack, Stephen J Savarino

A First in Human Clinical Trial Assessing the Safety and Immunogenicity of Two Intradermally Delivered Enterotoxigenic Escherichia coli CFA/I Fimbrial Tip Adhesin Antigens with and without Heat-Labile Enterotoxin with Mutation LT(R192G)

首次在人体临床试验中评估两种皮内递送的产肠毒素大肠杆菌 CFA/I 菌毛尖端粘附素抗原(含或不含突变 LT(R192G) 的热不稳定肠毒素)的安全性和免疫原性

Ramiro L Gutiérrez, Mark S Riddle, Chad K Porter, Milton Maciel Jr, Steven T Poole, Renee M Laird, Michelle Lane, George W Turiansky, Abel Jarell, Stephen J Savarino

Enhanced Immunogenicity and Protective Efficacy of a Campylobacter jejuni Conjugate Vaccine Coadministered with Liposomes Containing Monophosphoryl Lipid A and QS-21

空肠弯曲菌结合疫苗与含单磷酰脂质 A 和 QS-21 的脂质体联合给药增强免疫原性和保护效果

Amritha Ramakrishnan, Nina M Schumack, Christina L Gariepy, Heather Eggleston, Gladys Nunez, Nereyda Espinoza, Monica Nieto, Rosa Castillo, Jesus Rojas, Andrea J McCoy, Zoltan Beck, Gary R Matyas, Carl R Alving, Patricia Guerry, Frédéric Poly, Renee M Laird

Evaluation of the reactogenicity, adjuvanticity and antigenicity of LT(R192G) and LT(R192G/L211A) by intradermal immunization in mice

通过小鼠皮内免疫评价LT(R192G)和LT(R192G/L211A)的反应原性、佐剂性和抗原性

Milton Maciel Jr, Mark Smith, Steven T Poole, Renee M Laird, Julianne E Rollenhagen, Robert W Kaminski, Heather Wenzel, A Louis Bourgeois, Stephen J Savarino

Phase-Variable Changes in the Position of O-Methyl Phosphoramidate Modifications on the Polysaccharide Capsule of Campylobacter jejuni Modulate Serum Resistance

空肠弯曲菌多糖荚膜上 O-甲基磷酰胺修饰位置的相变变化调节血清阻力

Brittany Pequegnat, Renee M Laird, Cheryl P Ewing, Christina L Hill, Eman Omari, Frederic Poly, Mario A Monteiro, Patricia Guerry

Blk haploinsufficiency impairs the development, but enhances the functional responses, of MZ B cells

Blk 单倍体不足会损害 MZ B 细胞的发育,但会增强其功能反应

Elizabeth M Samuelson, Renee M Laird, Alexander C Maue, Rosemary Rochford, Sandra M Hayes

Unexpected role for the B cell-specific Src family kinase B lymphoid kinase in the development of IL-17-producing γδ T cells

细胞特异性 Src 家族激酶 B 淋巴样激酶在产生 IL-17 的 γδT 细胞发育中发挥意外作用

Renee M Laird, Karen Laky, Sandra M Hayes