日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Solution structures of the Shewanella woodyi H-NOX protein in the presence and absence of soluble guanylyl cyclase stimulator IWP-051

在有无可溶性鸟苷酸环化酶刺激剂 IWP-051 存在下,希瓦氏菌 H-NOX 蛋白的溶液结构

Chen, Cheng-Yu; Lee, Woonghee; Renhowe, Paul A; Jung, Joon; Montfort, William R

The CNS-Penetrant Soluble Guanylate Cyclase Stimulator CY6463 Reveals its Therapeutic Potential in Neurodegenerative Diseases

中枢神经系统渗透性可溶性鸟苷酸环化酶刺激剂 CY6463 揭示其在神经退行性疾病中的治疗潜力

Susana S Correia, Rajesh R Iyengar, Peter Germano, Kim Tang, Sylvie G Bernier, Chad D Schwartzkopf, Jenny Tobin, Thomas W-H Lee, Guang Liu, Sarah Jacobson, Andrew Carvalho, Glen R Rennie, Joon Jung, Paul A Renhowe, Elisabeth Lonie, Christopher J Winrow, John R Hadcock, Juli E Jones, Mark G Currie

Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase

发现刺激物与可溶性鸟苷酸环化酶血红素结构域中的保守口袋结合

Jessica A Wales, Cheng-Yu Chen, Linda Breci, Andrzej Weichsel, Sylvie G Bernier, James E Sheppeck 2nd, Robert Solinga, Takashi Nakai, Paul A Renhowe, Joon Jung, William R Montfort