日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SARS-CoV-2 and MERS-CoV disrupt host protein synthesis via nsp1 with differential effects on the integrated stress response

SARS-CoV-2 和 MERS-CoV 通过 nsp1 干扰宿主蛋白合成,对整合应激反应产生不同的影响。

Parenti, Nicholas A; Cusic, Renee; Renner, David M; Jackson, Nathaniel; Ye, Chengjin; Tan, Li Hui; Pfannenstiel, Jessica J; Fehr, Anthony R; Cohen, Noam A; Martinez-Sobrido, Luis; Burke, James M; Weiss, Susan R

Human alphacoronavirus replication and innate immune induction in airway culture systems.

人类甲型冠状病毒在气道培养系统中的复制和先天免疫诱导。

Fausto Alejandra, Otter Clayton J, Torres Leonel, Blomqvist Ebba K, Bracci Nicole, Renner David M, Tan Li Hui, Mooring Devon, Ebert Nadine, Trüeb Bettina, Thiel Volker, Cohen Noam A, Burke James M, Weiss Susan R

Modes of action of a small molecule antiviral compound targeting yellow fever virus NS4B protein

一种靶向黄热病毒NS4B蛋白的小分子抗病毒化合物的作用机制

Wang, Fuxuan; Gao, Zhao; Chen, Bo; Jiang, Zhengyuan; Renner, David M; Li, Jiaqi; Tolufashe, Gideon; Du, Yanming; Guo, Ju-Tao; Chang, Jinhong

Common Cold Coronavirus 229E Induces Higher Interferon Stimulating Gene Responses in Human Nasal Epithelial Cells from Patients with Chronic Rhinosinusitis with Polyposis

普通感冒冠状病毒229E可诱导慢性鼻窦炎伴息肉患者鼻上皮细胞中干扰素刺激基因反应增强

Sell, Elizabeth A; Tan, Li Hui; Renner, David M; Douglas, Jennifer; Lee, Robert J; Kohanski, Michael A; Bosso, John V; Kennedy, David W; Palmer, James N; Adappa, Nithin D; Weiss, Susan R; Cohen, Noam A

SARS-CoV-2 and MERS-CoV disrupt host protein synthesis via nsp1 with differential effects on the integrated stress response

SARS-CoV-2 和 MERS-CoV 通过 nsp1 干扰宿主蛋白合成,对整合应激反应产生不同的影响。

Parenti, Nicholas A; Cusic, Renee; Renner, David M; Jackson, Nathaniel; Ye, Chengjin; Tan, Li Hui; Pfannenstiel, Jessica J; Fehr, Anthony R; Cohen, Noam A; Martinez-Sobrido, Luis; Burke, James M; Weiss, Susan R

Interferon signaling in the nasal epithelium distinguishes among lethal and common cold coronaviruses and mediates viral clearance

鼻上皮细胞中的干扰素信号传导能够区分致命性冠状病毒和普通感冒冠状病毒,并介导病毒清除。

Otter, Clayton J; Renner, David M; Fausto, Alejandra; Tan, Li Hui; Cohen, Noam A; Weiss, Susan R

Activation of alveolar epithelial ER stress by β-coronavirus infection disrupts surfactant homeostasis in mice: implications for COVID-19 respiratory failure.

β冠状病毒感染激活肺泡上皮内质网应激,破坏小鼠肺表面活性物质稳态:对COVID-19呼吸衰竭的影响

Murthy Aditi, Rodriguez Luis R, Dimopoulos Thalia, Bui Sarah, Iyer Swati, Chavez Katrina, Tomer Yaniv, Abraham Valsamma, Cooper Charlotte, Renner David M, Katzen Jeremy B, Bentley Ian D, Ghadiali Samir N, Englert Joshua A, Weiss Susan R, Beers Michael F

BETACORONAVIRUSES DIFFERENTIALLY ACTIVATE THE INTEGRATED STRESS RESPONSE TO OPTIMIZE VIRAL REPLICATION IN LUNG DERIVED CELL LINES.

β冠状病毒通过差异性激活整合应激反应来优化肺源性细胞系中的病毒复制

Renner David M, Parenti Nicholas A, Weiss Susan R

SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes

SARS-CoV-2 可诱导呼吸道上皮细胞和心肌细胞中双链 RNA 介导的先天免疫反应。

Li, Yize; Renner, David M; Comar, Courtney E; Whelan, Jillian N; Reyes, Hanako M; Cardenas-Diaz, Fabian Leonardo; Truitt, Rachel; Tan, Li Hui; Dong, Beihua; Alysandratos, Konstantinos Dionysios; Huang, Jessie; Palmer, James N; Adappa, Nithin D; Kohanski, Michael A; Kotton, Darrell N; Silverman, Robert H; Yang, Wenli; Morrisey, Edward E; Cohen, Noam A; Weiss, Susan R

Zika virus employs the host antiviral RNase L protein to support replication factory assembly

寨卡病毒利用宿主抗病毒RNase L蛋白来支持复制工厂的组装。

Whelan, Jillian N; Parenti, Nicholas A; Hatterschide, Joshua; Renner, David M; Li, Yize; Reyes, Hanako M; Dong, Beihua; Perez, Erick R; Silverman, Robert H; Weiss, Susan R