日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

HLA-DQA1*05 Associates With Anti-Tumor Necrosis Factor Immunogenicity and Low Adalimumab Trough Concentrations in Inflammatory Bowel Disease Patients From the SERENE Ulcerative Colitis and Crohn's Disease Studies

来自SERENE溃疡性结肠炎和克罗恩病研究的炎症性肠病患者中,HLA-DQA1*05与抗肿瘤坏死因子免疫原性和阿达木单抗谷浓度低相关

Reppell, Mark; Zheng, Xiuwen; Dreher, Ingeborg; Blaes, Jonas; Regan, Elina; Haslberger, Tobias; Guay, Heath; Pivorunas, Valerie; Smaoui, Nizar

Author Correction: Genotyping, sequencing and analysis of 140,000 adults from Mexico City

作者更正:对墨西哥城14万名成年人进行基因分型、测序和分析

Ziyatdinov, Andrey; Torres, Jason; Alegre-Díaz, Jesús; Backman, Joshua; Mbatchou, Joelle; Turner, Michael; Gaynor, Sheila M; Joseph, Tyler; Zou, Yuxin; Liu, Daren; Wade, Rachel; Staples, Jeffrey; Panea, Razvan; Popov, Alex; Bai, Xiaodong; Balasubramanian, Suganthi; Habegger, Lukas; Lanche, Rouel; Lopez, Alex; Maxwell, Evan; Jones, Marcus; García-Ortiz, Humberto; Ramirez-Reyes, Raul; Santacruz-Benítez, Rogelio; Nag, Abhishek; Smith, Katherine R; Damask, Amy; Lin, Nan; Paulding, Charles; Reppell, Mark; Zöllner, Sebastian; Jorgenson, Eric; Salerno, William; Petrovski, Slavé; Overton, John; Reid, Jeffrey; Thornton, Timothy A; Abecasis, Gonçalo; Berumen, Jaime; Orozco-Orozco, Lorena; Collins, Rory; Baras, Aris; Hill, Michael R; Emberson, Jonathan R; Marchini, Jonathan; Kuri-Morales, Pablo; Tapia-Conyer, Roberto

Baseline Expression of Immune Gene Modules in Blood is Associated With Primary Response to Anti-TNF Therapy in Crohn's Disease Patients

血液中免疫基因模块的基线表达与克罗恩病患者对TNF抑制剂治疗的初始反应相关

Bai, Benjamin Y H; Reppell, Mark; Smaoui, Nizar; Waring, Jeffrey F; Pivorunas, Valerie; Guay, Heath; Lin, Simeng; Chanchlani, Neil; Bewshea, Claire; Goodhand, James R; Kennedy, Nicholas A; Ahmad, Tariq; Anderson, Carl A

Whole Blood DNA Methylation Changes Are Associated with Anti-TNF Drug Concentration in Patients with Crohn's Disease

克罗恩病患者全血DNA甲基化改变与抗TNF药物浓度相关

Lin, Simeng; Hannon, Eilis; Reppell, Mark; Waring, Jeffrey F; Smaoui, Nizar; Pivorunas, Valerie; Guay, Heath; Chanchlani, Neil; Bewshea, Claire; Bai, Benjamin Y H; Kennedy, Nicholas A; Goodhand, James R; Mill, Jonathan; Ahmad, Tariq

Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes

对英国生物银行394,841个外显子组中的数千种表型进行系统的单变异和基于基因的关联性检测

Karczewski, Konrad J; Solomonson, Matthew; Chao, Katherine R; Goodrich, Julia K; Tiao, Grace; Lu, Wenhan; Riley-Gillis, Bridget M; Tsai, Ellen A; Kim, Hye In; Zheng, Xiuwen; Rahimov, Fedik; Esmaeeli, Sahar; Grundstad, A Jason; Reppell, Mark; Waring, Jeff; Jacob, Howard; Sexton, David; Bronson, Paola G; Chen, Xing; Hu, Xinli; Goldstein, Jacqueline I; King, Daniel; Vittal, Christopher; Poterba, Timothy; Palmer, Duncan S; Churchhouse, Claire; Howrigan, Daniel P; Zhou, Wei; Watts, Nicholas A; Nguyen, Kevin; Nguyen, Huy; Mason, Cara; Farnham, Christopher; Tolonen, Charlotte; Gauthier, Laura D; Gupta, Namrata; MacArthur, Daniel G; Rehm, Heidi L; Seed, Cotton; Philippakis, Anthony A; Daly, Mark J; Davis, J Wade; Runz, Heiko; Miller, Melissa R; Neale, Benjamin M

An efficient algorithm for generating the internal branches of a Kingman coalescent

一种用于生成金曼合并算法内部分支的高效算法

Reppell, M; Zöllner, S

The impact of accelerating faster than exponential population growth on genetic variation

人口增长速度超过指数级增长速度对遗传变异的影响

Reppell, Mark; Boehnke, Michael; Zöllner, Sebastian

Analysis of rare variant population structure in Europeans explains differential stratification of gene-based tests

对欧洲人群中罕见变异群体结构的分析解释了基于基因检测结果的差异性分层。

Zawistowski, Matthew; Reppell, Mark; Wegmann, Daniel; St Jean, Pamela L; Ehm, Margaret G; Nelson, Matthew R; Novembre, John; Zöllner, Sebastian

FTEC: a coalescent simulator for modeling faster than exponential growth

FTEC:一种用于模拟超指数增长的合并模拟器

Reppell, Mark; Boehnke, Michael; Zöllner, Sebastian