APOBEC3B-mediated corruption of the tumor cell immunopeptidome induces heteroclitic neoepitopes for cancer immunotherapy
APOBEC3B 介导的肿瘤细胞免疫肽组破坏会诱导异质新表位用于癌症免疫治疗
期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-020-14568-7
Christopher B Driscoll #, Matthew R Schuelke #, Timothy Kottke, Jill M Thompson, Phonphimon Wongthida, Jason M Tonne, Amanda L Huff, Amber Miller, Kevin G Shim, Amy Molan, Cynthia Wetmore, Peter Selby, Adel Samson, Kevin Harrington, Hardev Pandha, Alan Melcher, Jose S Pulido, Reuben Harris, Laura Ev
信号转导
肿瘤
肿瘤细胞
Cell Depletion
Functional/Block/Neutralize
WB
Mouse
CTLA4