日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

DNA immunotherapy for recurrent respiratory papillomatosis (RRP): phase 1/2 study assessing efficacy, safety, and immunogenicity of INO-3107

DNA免疫疗法治疗复发性呼吸道乳头状瘤病(RRP):一项评估INO-3107疗效、安全性和免疫原性的1/2期研究

Morrow, Matthew P; Gillespie, Elisabeth; Sylvester, Albert; Amin, Milan R; Belafsky, Peter C; Best, Simon R; Friedman, Aaron D; Klein, Adam M; Lott, David G; Mau, Ted; Paniello, Randal C; Pransky, Seth M; Saba, Nabil F; Tan, Grace S; Wisotsky, Sadie; Marcus, Sarah A; Reuschel, Emma L; Reed, Katherine S; Weiner, David B; Dallas, Michael; Skolnik, Jeffrey M

Safety, tolerability, and immunogenicity of INO-4500, a synthetic DNA-based vaccine against Lassa virus, in a phase 1b clinical trial in healthy Ghanaian adults

在加纳健康成年人中开展的 1b 期临床试验中,研究人员评估了 INO-4500(一种合成 DNA 疫苗,用于预防拉沙病毒)的安全性、耐受性和免疫原性。

Koram, Kwadwo Ansah; Walker, Kathleen A; Orizu, Bonaventure; Marrero, Idania; Boyer, Jean; Yang, ShuPing; Broderick, Kate E; Kusi, Kwadwo Asamoah; Kyei-Baafour, Eric; Ofori, Ebenezer Addo; Pobee, Abigail; Adu-Amankwah, Susan; Amoakoh-Coleman, Mary; Amoakoh, Hannah Brown; Abuaku, Benjamin; Badji, Edem; Ntiri, Michael; Quaye, Lydia; Morrow, Matthew P; Sylvester, Albert J; Reuschel, Emma L; Gillespie, Elisabeth; Liebowitz, David; Humeau, Laurent M

Safety and Immunogenicity of an Anti-Zika Virus DNA Vaccine

抗寨卡病毒DNA疫苗的安全性和免疫原性

Tebas, Pablo; Roberts, Christine C; Muthumani, Kar; Reuschel, Emma L; Kudchodkar, Sagar B; Zaidi, Faraz I; White, Scott; Khan, Amir S; Racine, Trina; Choi, Hyeree; Boyer, Jean; Park, Young K; Trottier, Sylvie; Remigio, Celine; Krieger, Diane; Spruill, Susan E; Bagarazzi, Mark; Kobinger, Gary P; Weiner, David B; Maslow, Joel N

Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: A preliminary report of an open-label, Phase 1 clinical trial.

INO-4800 DNA疫苗对SARS-CoV-2的安全性和免疫原性:一项开放标签1期临床试验的初步报告

Tebas Pablo, Yang ShuPing, Boyer Jean D, Reuschel Emma L, Patel Ami, Christensen-Quick Aaron, Andrade Viviane M, Morrow Matthew P, Kraynyak Kimberly, Agnes Joseph, Purwar Mansi, Sylvester Albert, Pawlicki Jan, Gillespie Elisabeth, Maricic Igor, Zaidi Faraz I, Kim Kevin Y, Dia Yaya, Frase Drew, Pezzoli Patrick, Schultheis Katherine, Smith Trevor R F, Ramos Stephanie J, McMullan Trevor, Buttigieg Karen, Carroll Miles W, Ervin John, Diehl Malissa C, Blackwood Elliott, Mammen Mammen P, Lee Jessica, Dallas Michael J, Brown Ami Shah, Shea Jacqueline E, Kim J Joseph, Weiner David B, Broderick Kate E, Humeau Laurent M

Intradermal delivery of a synthetic DNA vaccine protects macaques from Middle East respiratory syndrome coronavirus

皮内注射合成DNA疫苗可保护猕猴免受中东呼吸综合征冠状病毒感染

Patel, Ami; Reuschel, Emma L; Xu, Ziyang; Zaidi, Faraz I; Kim, Kevin Y; Scott, Dana P; Mendoza, Janess; Ramos, Stephanie; Stoltz, Regina; Feldmann, Friederike; Okumura, Atsushi; Meade-White, Kimberly; Haddock, Elaine; Thomas, Tina; Rosenke, Rebecca; Lovaglio, Jamie; Hanley, Patrick W; Saturday, Greg; Muthumani, Kar; Feldmann, Heinz; Humeau, Laurent M; Broderick, Kate E; Weiner, David B

A novel synthetic DNA vaccine elicits protective immune responses against Powassan virus

一种新型合成DNA疫苗可诱导针对波瓦桑病毒的保护性免疫反应

Choi, Hyeree; Kudchodkar, Sagar B; Ho, Michelle; Reuschel, Emma L; Reynolds, Erin; Xu, Ziyang; Bordoloi, Devivasha; Ugen, Kenneth E; Tebas, Pablo; Kim, Joseph; Abdel-Mohsen, Mohamed; Thangamani, Saravanan; Weiner, David B; Muthumani, Kar

Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial

抗中东呼吸综合征冠状病毒DNA疫苗的安全性和免疫原性:一项1期、开放标签、单臂、剂量递增试验

Modjarrad, Kayvon; Roberts, Christine C; Mills, Kristin T; Castellano, Amy R; Paolino, Kristopher; Muthumani, Kar; Reuschel, Emma L; Robb, Merlin L; Racine, Trina; Oh, Myoung-Don; Lamarre, Claude; Zaidi, Faraz I; Boyer, Jean; Kudchodkar, Sagar B; Jeong, Moonsup; Darden, Janice M; Park, Young K; Scott, Paul T; Remigio, Celine; Parikh, Ajay P; Wise, Megan C; Patel, Ami; Duperret, Elizabeth K; Kim, Kevin Y; Choi, Hyeree; White, Scott; Bagarazzi, Mark; May, Jeanine M; Kane, Deborah; Lee, Hyojin; Kobinger, Gary; Michael, Nelson L; Weiner, David B; Thomas, Stephen J; Maslow, Joel N

Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility

CXCR4基因变异与幼年特发性关节炎易感性相关

Finkel, Terri H; Li, Jin; Wei, Zhi; Wang, Wei; Zhang, Haitao; Behrens, Edward M; Reuschel, Emma L; Limou, Sophie; Wise, Carol; Punaro, Marilynn; Becker, Mara L; Munro, Jane E; Flatø, Berit; Førre, Øystein; Thompson, Susan D; Langefeld, Carl D; Glass, David N; Glessner, Joseph T; Kim, Cecilia E; Frackelton, Edward; Shivers, Debra K; Thomas, Kelly A; Chiavacci, Rosetta M; Hou, Cuiping; Xu, Kexiang; Snyder, James; Qiu, Haijun; Mentch, Frank; Wang, Kai; Winkler, Cheryl A; Lie, Benedicte A; Ellis, Justine A; Hakonarson, Hakon

Co-Administration of Molecular Adjuvants Expressing NF-Kappa B Subunit p65/RelA or Type-1 Transactivator T-bet Enhance Antigen Specific DNA Vaccine-Induced Immunity

联合使用表达 NF-κB 亚基 p65/RelA 或 1 型转录激活因子 T-bet 的分子佐剂可增强抗原特异性 DNA 疫苗诱导的免疫力

Shedlock, Devon J; Tingey, Colleen; Mahadevan, Lavanya; Hutnick, Natalie; Reuschel, Emma L; Kudchodkar, Sagar; Flingai, Seleeke; Yan, Jenny; Kim, Joseph J; Ugen, Kenneth E; Weiner, David B; Muthumani, Kar