日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Encapsulation of mRNA in Therapeutics Like Lipid Nanoparticles Probed by Deep-UV Resonance Raman Spectroscopy

利用深紫外共振拉曼光谱探测脂质纳米颗粒等治疗剂中mRNA的封装

Jin, Sila; Reverdatto, Sergei V; Ermolenkov, Vladimir V; Shekhtman, Alexander; Jung, Young Mee; Lednev, Igor K

RAGE-mediated activation of the formin DIAPH1 and human macrophage inflammation are inhibited by a small molecule antagonist

小分子拮抗剂可抑制 RAGE 介导的 formin DIAPH1 激活和人巨噬细胞炎症。

Theophall, Gregory G; Manigrasso, Michaele B; Nazarian, Parastou; Premo, Aaron; Reverdatto, Sergey; Yepuri, Gautham; Burz, David S; Vanegas, Sally M; Mangar, Kaamashri; Zhao, Yanan; Li, Huilin; DeVita, Robert J; Ramasamy, Ravichandran; Schmidt, Ann Marie; Shekhtman, Alexander

Negative cooperativity regulates ligand activation of DIAPH1 and other diaphanous related formins.

负协同性调节 DIAPH1 和其他 diaphanous 相关 formin 的配体激活

Theophall G G, Premo A, Reverdatto S, Omojowolo E, Nazarian P, Burz D S, Ramasamy R, Schmidt A M, Shekhtman A

In Situ Stability Test for mRNA Vaccines Based on Deep-UV Resonance Raman Spectroscopy.

基于深紫外共振拉曼光谱的mRNA疫苗原位稳定性测试

Almehmadi Lamyaa M, Reverdatto Sergei V, Ermolenkov Vladimir V, Shekhtman Alexander, Lednev Igor K

DIAPH1-MFN2 interaction regulates mitochondria-SR/ER contact and modulates ischemic/hypoxic stress

DIAPH1-MFN2相互作用调节线粒体-肌浆网/内质网接触并调节缺血/缺氧应激

Gautham Yepuri ,Lisa M Ramirez ,Gregory G Theophall ,Sergei V Reverdatto ,Nosirudeen Quadri ,Syed Nurul Hasan ,Lei Bu ,Devi Thiagarajan ,Robin Wilson ,Raquel López Díez ,Paul F Gugger ,Kaamashri Mangar ,Navneet Narula ,Stuart D Katz ,Boyan Zhou ,Huilin Li ,Aleksandr B Stotland ,Roberta A Gottlieb ,Ann Marie Schmidt ,Alexander Shekhtman ,Ravichandran Ramasamy

Disruption of the productive encounter complex results in dysregulation of DIAPH1 activity

生产性遭遇复合体的破坏导致 DIAPH1 活性失调

Gregory G Theophall, Lisa M S Ramirez, Aaron Premo, Sergey Reverdatto, Michaele B Manigrasso, Gautham Yepuri, David S Burz, Ravichandran Ramasamy, Ann Marie Schmidt, Alexander Shekhtman

Messenger RNA in lipid nanoparticles rescues HEK 293 cells from lipid-induced mitochondrial dysfunction as studied by real time pulse chase NMR, RTPC-NMR, spectroscopy

实时脉冲追踪核磁共振(RTPC-NMR)光谱研究表明,脂质纳米颗粒中的信使RNA能够挽救HEK 293细胞免受脂质诱导的线粒体功能障碍。

Sciolino, Nicholas; Reverdatto, Sergey; Premo, Aaron; Breindel, Leonard; Yu, Jianchao; Theophall, Gregory; Burz, David S; Liu, Anna; Sulchek, Todd; Schmidt, Ann Marie; Ramasamy, Ravichandran; Shekhtman, Alexander

Developmental and Injury-induced Changes in DNA Methylation in Regenerative versus Non-regenerative Regions of the Vertebrate Central Nervous System

脊椎动物中枢神经系统再生区域和非再生区域的 DNA 甲基化发育和损伤引起的变化

Sergei Reverdatto, Aparna Prasad, Jamie L Belrose, Xiang Zhang, Morgan A Sammons, Kurt M Gibbs, Ben G Szaro

Small-molecule antagonism of the interaction of the RAGE cytoplasmic domain with DIAPH1 reduces diabetic complications in mice

RAGE 胞质结构域与 DIAPH1 相互作用的小分子拮抗剂可减少小鼠的糖尿病并发症

Michaele B Manigrasso, Piul Rabbani, Lander Egaña-Gorroño, Nosirudeen Quadri, Laura Frye, Boyan Zhou, Sergey Reverdatto, Lisa S Ramirez, Stephen Dansereau, Jinhong Pan, Huilin Li, Vivette D D'Agati, Ravichandran Ramasamy, Robert J DeVita, Alexander Shekhtman, Ann Marie Schmidt

Receptor for Advanced Glycation End Products (RAGE) and Mechanisms and Therapeutic Opportunities in Diabetes and Cardiovascular Disease: Insights From Human Subjects and Animal Models

晚期糖基化终产物受体(RAGE)及其在糖尿病和心血管疾病中的作用机制和治疗机遇:来自人体受试者和动物模型的启示

Egaña-Gorroño, Lander; López-Díez, Raquel; Yepuri, Gautham; Ramirez, Lisa S; Reverdatto, Sergey; Gugger, Paul F; Shekhtman, Alexander; Ramasamy, Ravichandran; Schmidt, Ann Marie