日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Quinpirole inhibits levodopa-induced dyskinesias at structural and behavioral levels: Efficacy negated by co-administration of isradipine

喹吡罗在结构和行为层面抑制左旋多巴诱发的运动障碍:与伊拉地平合用会抵消其疗效。

Collier, Timothy J; Begg, Lauren; Stancati, Jennifer A; Mercado, Natosha M; Sellnow, Rhyomi C; Sandoval, Ivette M; Sortwell, Caryl E; Steece-Collier, Kathy

Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease

纹状体 Nurr1 促进帕金森病大鼠模型的运动障碍状态并加剧左旋多巴诱发的运动障碍

Rhyomi C Sellnow, Kathy Steece-Collier, Feras Altwal, Ivette M Sandoval, Jeffrey H Kordower, Timothy J Collier, Caryl E Sortwell, Anthony R West, Fredric P Manfredsson

Striatal Nurr1, but not FosB expression links a levodopa-induced dyskinesia phenotype to genotype in Fisher 344 vs. Lewis hemiparkinsonian rats

纹状体 Nurr1 表达(而非 FosB 表达)将左旋多巴诱导的运动障碍表型与 Fisher 344 和 Lewis 半侧帕金森病大鼠的基因型联系起来。

Steece-Collier, Kathy; Collier, Timothy J; Lipton, Jack W; Stancati, Jennifer A; Winn, Mary E; Cole-Strauss, Allyson; Sellnow, Rhyomi; Conti, Melissa M; Mercado, Natosha M; Nillni, Eduardo A; Sortwell, Caryl E; Manfredsson, Fredric P; Bishop, Christopher

Regulation of dopamine neurotransmission from serotonergic neurons by ectopic expression of the dopamine D2 autoreceptor blocks levodopa-induced dyskinesia

通过多巴胺 D2 自身受体的异位表达来调节来自血清素能神经元的多巴胺神经传递,从而阻断左旋多巴引起的运动障碍

Rhyomi C Sellnow, Jordan H Newman, Nicole Chambers, Anthony R West, Kathy Steece-Collier, Ivette M Sandoval, Matthew J Benskey, Christopher Bishop, Fredric P Manfredsson

Silencing Alpha Synuclein in Mature Nigral Neurons Results in Rapid Neuroinflammation and Subsequent Toxicity

沉默成熟黑质神经元中的 α-突触核蛋白会导致快速的神经炎症和随后的毒性

Matthew J Benskey, Rhyomi C Sellnow, Ivette M Sandoval, Caryl E Sortwell, Jack W Lipton, Fredric P Manfredsson

Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS

合理设计的 AAV 衣壳可改善中枢神经系统中的转导和体积扩散

Nicholas M Kanaan, Rhyomi C Sellnow, Sanford L Boye, Ben Coberly, Antonette Bennett, Mavis Agbandje-McKenna, Caryl E Sortwell, William W Hauswirth, Shannon E Boye, Fredric P Manfredsson

Loss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons

α-突触核蛋白的缺失不会影响啮齿动物神经元的线粒体生物能量学

Divya Pathak, Amandine Berthet, Jacob T Bendor, Katharine Yu, Rhyomi C Sellnow, Adam L Orr, Mai K Nguyen, Robert H Edwards, Fredric P Manfredsson, Ken Nakamura