日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lgmn targets two distinct GPCRs, PAR2 and µ-OR1, and induces cell death in acute lymphoblastic leukemia through an intracellular Ca²⁺ imbalance triggered by ER Ca²⁺ release.

Lgmn 靶向两种不同的 GPCR,PAR2 和 μ-OR1,并通过内质网 Ca²⁺ 释放引发的细胞内 Ca²⁺ 失衡诱导急性淋巴细胞白血病细胞死亡。

Lee Jung Kwon, Riabowol Karl, Lee Ki-Young

A recently evolved domain of the human ING1 epigenetic regulator targets mitochondria and induces senescence

人类ING1表观遗传调控因子最近进化出的一个结构域靶向线粒体并诱导衰老

Bertschmann, Jessica; Liu, Grace; Djamshidi, Mahbod; Heshmatazad, Katy; Romanov, Yury; Dhaliwahl, Jasleen; Hojjat, Hamed; Yang, Yang; de Koning, A P Jason; Riabowol, Karl; Hill, Alexander

FAME-CRISPR improves CRISPR-Cas9 genome editing via HDAC inhibition and engineered virus-like particle delivery.

FAME-CRISPR 通过 HDAC 抑制和工程化病毒样颗粒递送来改进 CRISPR-Cas9 基因组编辑。

Djamshidi Mahbod, Hill Alexander, Heshmatzad Katayoun, Langley Jethro, Krowicki Hokan, Ali Motamed, Yang Yang, Tanida Ryota, Abdul-Careem Mohamed Faizal, Billon Pierre, Riabowol Karl

Protocol for enhancing CRISPR-Cas9 genome editing using histone deacetylase inhibition and engineered virus-like particle delivery

利用组蛋白去乙酰化酶抑制剂和工程化病毒样颗粒递送增强 CRISPR-Cas9 基因组编辑的方案

Djamshidi, Mahbod; Tanida, Ryota; Heshmatzad, Katayoun; Krowicki, Hokan; Hill, Alexander; Yang, Yang; Riabowol, Karl

L-asparaginase is a PAR2 N-terminal protease that unmasks the PAR2 tethered ligand.

L-天冬酰胺酶是一种 PAR2 N 端蛋白酶,可暴露 PAR2 连接的配体

Lee Jung Kwon, Riabowol Karl, Wang Xidi, Lee Ki-Young

Functions of TIP60/NuA4 Complex Subunits in Cell Differentiation

TIP60/NuA4复合物亚基在细胞分化中的功能

Hashemi, Fatemeh; Nourozi, Aida; Loushab, Mojtaba Shaban; Riabowol, Karl

Loss of ING3 in the Prostate Leads to Activation of DNA Damage Repair Markers.

前列腺中 ING3 的缺失会导致 DNA 损伤修复标记的激活

Lang Viktor, Barones Lisa, Hu ShiTing Misaki, Hashemi Fatemeh, Blote Karen, Riabowol Karl, Fink Dieter

Tissue-specific localization of the ING4 targeting subunit of the HBO1 histone acetyltransferase in the cytoplasm and nucleus of secretory cells.

HBO1 组蛋白乙酰转移酶的 ING4 靶向亚基在分泌细胞的细胞质和细胞核中具有组织特异性定位

Dantas Arthur, Shueili Buthaina Al, Park Jeongah, Abdullah Suleyman, Bertschmann Jessica, Krowicki Hokan, Djamshidi Mahbod, Yang Yang, Blote Karen, Thalappilly Subhash, Riabowol Karl

Histone Acetyltransferases and Stem Cell Identity

组蛋白乙酰转移酶与干细胞身份

He, Ruicen; Dantas, Arthur; Riabowol, Karl

Senescence and Apoptosis: Architects of Mammalian Development

衰老与细胞凋亡:哺乳动物发育的架构师

Wanner, Emma; Thoppil, Harikrishnan; Riabowol, Karl