日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Assessment of drug permeability using a small airway microphysiological system.

利用小气道微生理系统评估药物渗透性

Geiger Robert M, Rahman Shekh M, Rashid Roni Md Shadiqur, Sullenberger Catherine, Mistry Sabyasachy, Shea Katherine, Tariq Isra, Ismaiel Omnia A, Matta Murali K, Hyland Paula L, Berdichevski Sasha, Ribeiro Alexandre J S, Blinova Ksenia, Jiang Wenlei, Walenga Ross L, Newman Bryan, Volpe Donna A, Ford Kevin A

A 3D Model of the Human Lung Airway for Evaluating Permeability of Inhaled Drugs

用于评估吸入药物渗透性的人体肺气道三维模型

Rahman, Shekh M; Geiger, Robert M; Roni, Md Shadiqur Rashid; Tariq, Isra; Ismaiel, Omnia; Matta, Murali K; Shea, Katherine; Bruckner, Dylan; Jiang, Wenlei; Walenga, Ross; Newman, Bryan; Hyland, Paula L; Ribeiro, Alexandre J S; Florian, Jeffrey; Blinova, Ksenia; Ford, Kevin A

Nonclinical Human Cardiac New Approach Methodologies (NAMs) Predict Vanoxerine-Induced Proarrhythmic Potential.

非临床人类心脏新方法(NAMs)预测万诺昔林诱发的致心律失常潜力

Garcia M Iveth, Bhardwaj Bhavya, Dame Keri, Charwat Verena, Siemons Brian A, Goswami Ishan, Ismaiel Omnia A, Mistry Sabyasachy, Feaster Tromondae K, Healy Kevin E, Ribeiro Alexandre J S, Blinova Ksenia

Reproducibility of drug-induced effects on the contractility of an engineered heart tissue derived from human pluripotent stem cells

药物对源自人类多能干细胞的工程化心脏组织收缩力的影响的可重复性

Arefin, Ayesha; Mendoza, Melissa; Dame, Keri; Garcia, M Iveth; Strauss, David G; Ribeiro, Alexandre J S

IVIVE: Facilitating the Use of In Vitro Toxicity Data in Risk Assessment and Decision Making

IVIVE:促进体外毒性数据在风险评估和决策中的应用

Chang, Xiaoqing; Tan, Yu-Mei; Allen, David G; Bell, Shannon; Brown, Paul C; Browning, Lauren; Ceger, Patricia; Gearhart, Jeffery; Hakkinen, Pertti J; Kabadi, Shruti V; Kleinstreuer, Nicole C; Lumen, Annie; Matheson, Joanna; Paini, Alicia; Pangburn, Heather A; Petersen, Elijah J; Reinke, Emily N; Ribeiro, Alexandre J S; Sipes, Nisha; Sweeney, Lisa M; Wambaugh, John F; Wange, Ronald; Wetmore, Barbara A; Mumtaz, Moiz

CRISPR/Cas9-based targeting of fluorescent reporters to human iPSCs to isolate atrial and ventricular-specific cardiomyocytes

利用CRISPR/Cas9技术将荧光报告基因靶向人类iPSCs,以分离心房和心室特异性心肌细胞

Chirikian, Orlando; Goodyer, William R; Dzilic, Elda; Serpooshan, Vahid; Buikema, Jan W; McKeithan, Wesley; Wu, HaoDi; Li, Guang; Lee, Soah; Merk, Markus; Galdos, Francisco; Beck, Aimee; Ribeiro, Alexandre J S; Paige, Sharon; Mercola, Mark; Wu, Joseph C; Pruitt, Beth L; Wu, Sean M

Liver Microphysiological Systems for Predicting and Evaluating Drug Effects

肝脏微生理系统在预测和评价药物效应中的应用

Ribeiro, Alexandre J S; Yang, Xinning; Patel, Vikram; Madabushi, Rajnikanth; Strauss, David G

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-Cardiomyocytes

体外细胞测试平台在药物早期研发中检测药物诱导正性肌力效应的考量。第二部分:利用人诱导多能干细胞来源的心肌细胞设计和构建具有生理相关性的微系统以检测心脏收缩力

Ribeiro, Alexandre J S; Guth, Brian D; Engwall, Michael; Eldridge, Sandy; Foley, C Michael; Guo, Liang; Gintant, Gary; Koerner, John; Parish, Stanley T; Pierson, Jennifer B; Brock, Mathew; Chaudhary, Khuram W; Kanda, Yasunari; Berridge, Brian

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Adverse Drug-Induced Inotropic Effects in Early Drug Development. Part 1: General Considerations for Development of Novel Testing Platforms

早期药物研发中用于检测药物诱导的不良正性肌力效应的体外细胞测试平台的考量因素。第一部分:新型测试平台开发的一般性考量因素

Guth, Brian D; Engwall, Michael; Eldridge, Sandy; Foley, C Michael; Guo, Liang; Gintant, Gary; Koerner, John; Parish, Stanley T; Pierson, Jennifer B; Ribeiro, Alexandre J S; Zabka, Tanja; Chaudhary, Khuram W; Kanda, Yasunari; Berridge, Brian

Multi-Imaging Method to Assay the Contractile Mechanical Output of Micropatterned Human iPSC-Derived Cardiac Myocytes

用于检测微图案化人诱导多能干细胞衍生心肌细胞收缩机械输出的多成像方法

Ribeiro, Alexandre J S; Schwab, Olivier; Mandegar, Mohammad A; Ang, Yen-Sin; Conklin, Bruce R; Srivastava, Deepak; Pruitt, Beth L