Bioisosteric Replacement of Amides with 1,2,3-Triazoles Improves Dopamine D4 Receptor Ligand Pharmacokinetics
用1,2,3-三唑类化合物生物等排取代酰胺类化合物可改善多巴胺D4受体配体的药代动力学
期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.5c00646
Alkhatib, Mohammad; Jakobs, Franziska M; Hanson, John N; Nilson, Ashley N; Moritz, Amy E; Li, Tian; Faibille, Afua B; Bourn, Lindsay A; Ramdhan, Peter A; Ricchezza, Joseph 4th; Jordan, Shannon; Panasis, Diandra; Nguyen, Norman; Kasarla, Nitish; Wang, Bryant; Garcia, Sergio Sola; Saez, Julianna; Paule, James; Lee, Chae Bin; Rais, Rana; Slusher, Barbara S; Sibley, David R; Li, Chenglong; Keck, Thomas M; Boateng, Comfort A
