Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes.
化学遗传筛选发现石胆酸是一种抗衰老化合物,它通过调节管家长寿保证过程,以不依赖于 TOR 的方式延长酵母的寿命
期刊:Aging-Us
影响因子:3.9
doi:10.18632/aging.100168
Goldberg Alexander A, Richard Vincent R, Kyryakov Pavlo, Bourque Simon D, Beach Adam, Burstein Michelle T, Glebov Anastasia, Koupaki Olivia, Boukh-Viner Tatiana, Gregg Christopher, Juneau Mylène, English Ann M, Thomas David Y, Titorenko Vladimir I