日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Measurement of CYP1A2 and CYP3A4 activity by a simplified Geneva cocktail approach in a cohort of free-living individuals: a pilot study.

采用简化的日内瓦鸡尾酒法对自由生活人群进行 CYP1A2 和 CYP3A4 活性测定:一项试点研究

Sobsey Constance A, Mady Noor, Richard Vincent R, LeBlanc Andre, Zakharov Thomas, Borchers Christoph H, Jagoe R Thomas

Early Prediction of COVID-19 Patient Survival by Targeted Plasma Multi-Omics and Machine Learning

利用靶向血浆多组学和机器学习早期预测新冠肺炎患者的生存率

Richard, Vincent R; Gaither, Claudia; Popp, Robert; Chaplygina, Daria; Brzhozovskiy, Alexander; Kononikhin, Alexey; Mohammed, Yassene; Zahedi, René P; Nikolaev, Evgeny N; Borchers, Christoph H

Direct and Precise Measurement of Bevacizumab Levels in Human Plasma Based on Controlled Methionine Oxidation and Multiple Reaction Monitoring

基于受控蛋氨酸氧化和多反应监测的贝伐珠单抗在人血浆中浓度的直接精确测定

Gaspar, Vanessa P; Ibrahim, Sahar; Sobsey, Constance A; Richard, Vincent R; Spatz, Alan; Zahedi, René P; Borchers, Christoph H

Caloric restriction delays yeast chronological aging by remodeling carbohydrate and lipid metabolism, altering peroxisomal and mitochondrial functionalities, and postponing the onsets of apoptotic and liponecrotic modes of regulated cell death.

热量限制通过重塑碳水化合物和脂质代谢、改变过氧化物酶体和线粒体功能以及推迟凋亡和脂质坏死等受调控细胞死亡方式的发生,来延缓酵母的自然衰老

Arlia-Ciommo Anthony, Leonov Anna, Beach Adam, Richard Vincent R, Bourque Simon D, Burstein Michelle T, Kyryakov Pavlo, Gomez-Perez Alejandra, Koupaki Olivia, Feldman Rachel, Titorenko Vladimir I

Macromitophagy, neutral lipids synthesis, and peroxisomal fatty acid oxidation protect yeast from "liponecrosis", a previously unknown form of programmed cell death.

巨噬细胞自噬、中性脂质合成和过氧化物酶体脂肪酸氧化保护酵母免受“脂质坏死”的影响,这是一种以前未知的程序性细胞死亡形式

Sheibani Sara, Richard Vincent R, Beach Adam, Leonov Anna, Feldman Rachel, Mattie Sevan, Khelghatybana Leila, Piano Amanda, Greenwood Michael, Vali Hojatollah, Titorenko Vladimir I

Lithocholic acid extends longevity of chronologically aging yeast only if added at certain critical periods of their lifespan.

只有在酵母生命周期的某些关键时期添加石胆酸,才能延长酵母的寿命

Burstein Michelle T, Kyryakov Pavlo, Beach Adam, Richard Vincent R, Koupaki Olivia, Gomez-Perez Alejandra, Leonov Anna, Levy Sean, Noohi Forough, Titorenko Vladimir I

Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes.

化学遗传筛选发现石胆酸是一种抗衰老化合物,它通过调节管家长寿保证过程,以不依赖于 TOR 的方式延长酵母的寿命

Goldberg Alexander A, Richard Vincent R, Kyryakov Pavlo, Bourque Simon D, Beach Adam, Burstein Michelle T, Glebov Anastasia, Koupaki Olivia, Boukh-Viner Tatiana, Gregg Christopher, Juneau Mylène, English Ann M, Thomas David Y, Titorenko Vladimir I