日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Down-regulation of AKT proteins slows the growth of mutant-KRAS pancreatic tumors

AKT 蛋白的下调减缓了 KRAS 突变型胰腺肿瘤的生长

Chuankai Chen, Ya-Ping Jiang, Inchul You, Nathanael S Gray, Richard Z Lin

Intercellular delivery of therapeutic oligonucleotides

治疗性寡核苷酸的细胞间递送

Virginijus Valiunas, Chris Gordon, Laima Valiuniene, Daniel Devine, Richard Z Lin, Ira S Cohen, Peter R Brink

Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin

TRIM21 的缺失可通过抑制化疗药物阿霉素引起的铁死亡来减轻心脏毒性

Kai Hou, Jianliang Shen, Junrong Yan, Chuannan Zhai, Jingxia Zhang, Ji-An Pan, Ye Zhang, Yaping Jiang, Yongbo Wang, Richard Z Lin, Hongliang Cong, Shenglan Gao, Wei-Xing Zong

Regulation of HCN2 Current by PI3K/Akt Signaling

PI3K/Akt 信号调节 HCN2 电流

Zhongju Lu, Hong Zhan Wang, Chris R Gordon, Lisa M Ballou, Richard Z Lin, Ira S Cohen

Tumor-intrinsic PIK3CA represses tumor immunogenecity in a model of pancreatic cancer

肿瘤内在的PIK3CA在胰腺癌模型中抑制肿瘤免疫原性

Nithya Sivaram ,Patrick A McLaughlin ,Han V Han ,Oleksi Petrenko ,Ya-Ping Jiang ,Lisa M Ballou ,Kien Pham ,Chen Liu ,Adrianus Wm van der Velden ,Richard Z Lin

CEMIP upregulates BiP to promote breast cancer cell survival in hypoxia

CEMIP 上调 BiP 促进乳腺癌细胞在缺氧条件下存活

Anna Banach, Ya-Ping Jiang, Eric Roth, Cem Kuscu, Jian Cao, Richard Z Lin

Phospholipase D2 loss results in increased blood pressure via inhibition of the endothelial nitric oxide synthase pathway

磷脂酶 D2 损失通过抑制内皮一氧化氮合酶途径导致血压升高

Rochelle K Nelson, Jiang Ya-Ping, John Gadbery, Danya Abedeen, Nicole Sampson, Richard Z Lin, Michael A Frohman

Activation of Gαq in Cardiomyocytes Increases Vps34 Activity and Stimulates Autophagy

心肌细胞中 Gαq 的激活会增加 Vps34 活性并刺激自噬

Shengnan Liu, Ya-Ping Jiang, Lisa M Ballou, Wei-Xing Zong, Richard Z Lin

TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis

TRIM21 泛素化 SQSTM1/p62 并抑制蛋白质封存以调节氧化还原稳态

Ji-An Pan, Yu Sun, Ya-Ping Jiang, Alex J Bott, Nadia Jaber, Zhixun Dou, Bin Yang, Juei-Suei Chen, Joseph M Catanzaro, Chunying Du, Wen-Xing Ding, Maria T Diaz-Meco, Jorge Moscat, Keiko Ozato, Richard Z Lin, Wei-Xing Zong

Increased persistent sodium current due to decreased PI3K signaling contributes to QT prolongation in the diabetic heart

由于 PI3K 信号传导减少导致持续性钠电流增加,导致糖尿病心脏 QT 间期延长

Zhongju Lu, Ya-Ping Jiang, Chia-Yen C Wu, Lisa M Ballou, Shengnan Liu, Eileen S Carpenter, Michael R Rosen, Ira S Cohen, Richard Z Lin