日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Gluebodies Offer a Route To Improve Crystal Reliability and Diversity through Transferable Nanobody Mutations That Introduce Constitutive Close Contacts

胶体提供了一种通过可转移的纳米抗体突变来提高晶体可靠性和多样性的途径,这些突变引入了组成性的紧密接触。

Ye, Mingda; Makola, Mpho; Richards, Mark W; Newman, Joseph A; Fairhead, Michael; Burgess, Selena G; Wu, Zhihuang; Maclean, Elizabeth; Wright, Nathan D; Koekemoer, Lizbé; Thompson, Andrew; Bezerra, Gustavo Arruda; Yi, Gangshun; Li, Huanyu; Rangel, Victor L; Mamalis, Dimitrios; Aitkenhead, Hazel; Davis, Benjamin G; Gilbert, Robert J C; Duerr, Katharina L; Bayliss, Richard; Gileadi, Opher; von Delft, Frank

Structural characterization and inhibition of the interaction between ch-TOG and TACC3.

ch-TOG 与 TACC3 相互作用的结构表征和抑制

Shelford James, Burgess Selena G, Rostkova Elena, Richards Mark W, Larocque Gabrielle, Sampson Josephina, Tiede Christian, Fielding Alistair J, Daviter Tina, Tomlinson Darren C, Calabrese Antonio N, Pfuhl Mark, Bayliss Richard, Royle Stephen J

Exploring the dynamics and interactions of the N-myc transactivation domain through solution nuclear magnetic resonance spectroscopy

利用溶液核磁共振波谱法探索N-myc转录激活结构域的动力学和相互作用

Rejnowicz, Ewa; Batchelor, Matthew; Leen, Eoin; Ahangar, Mohd Syed; Burgess, Selena G; Richards, Mark W; Kalverda, Arnout P; Bayliss, Richard

Molecular mechanisms that underpin EML4-ALK driven cancers and their response to targeted drugs

EML4-ALK驱动型癌症的分子机制及其对靶向药物的反应

Bayliss, Richard; Choi, Jene; Fennell, Dean A; Fry, Andrew M; Richards, Mark W

A closed conformation of the Caenorhabditis elegans separase-securin complex

秀丽隐杆线虫分离酶-安全蛋白复合物的闭合构象

Bachmann, Gudrun; Richards, Mark W; Winter, Anja; Beuron, Fabienne; Morris, Edward; Bayliss, Richard

Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization.

Nek7通过Nek9结合和诱导二聚化而被激活的机制基础

Haq Tamanna, Richards Mark W, Burgess Selena G, Gallego Pablo, Yeoh Sharon, O'Regan Laura, Reverter David, Roig Joan, Fry Andrew M, Bayliss Richard

An autoinhibitory tyrosine motif in the cell-cycle-regulated Nek7 kinase is released through binding of Nek9.

细胞周期调控的 Nek7 激酶中的自身抑制酪氨酸基序通过 Nek9 的结合而被释放

Richards Mark W, O'Regan Laura, Mas-Droux Corine, Blot Joelle M Y, Cheung Jack, Hoelder Swen, Fry Andrew M, Bayliss Richard

Insights into the conformational variability and regulation of human Nek2 kinase

对人类Nek2激酶构象变异性和调控的深入研究

Westwood, Isaac; Cheary, Donna-Marie; Baxter, Joanne E; Richards, Mark W; van Montfort, Rob L M; Fry, Andrew M; Bayliss, Richard