日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SARS-CoV-2 vaccines elicit differential Fc effector functions.

SARS-CoV-2疫苗会引发不同的Fc效应功能

Manamela Nelia P, Motsoeneng Boitumelo M, Spencer Holly, Hermanus Tandile, Mzindle Nonkululeko, Ayres Frances, Makhado Zanele, Serage Rudolph, Gray Glenda G, Bekker Linda-Gail, Madhi Shabir A, Moore Penny L, Richardson Simone I

Glycan-reactive antibodies isolated from human HIV-1 vaccine trial participants show broad pathogen cross-reactivity

从人类HIV-1疫苗试验参与者中分离出的糖反应性抗体显示出广泛的病原体交叉反应性。

Jamieson, Parker J; Shen, Xiaoying; Abu-Shmais, Alexandra A; Wasdin, Perry T; Janowska, Katarzyna; Edwards, Robert J; Scapellato, Garrett; Bukenya, Maurice; Bass, Lindsay E; Richardson, Simone I; Manamela, Nelia P; Liu, Shuying; Barr, Maggie; Adams, Lindsey; Paola Velez-Castro, Cristina; McCarthy, Caitlin; Alexander, Caroline A; Gillespie, Rebecca A; Mimms, Jessica; Suryadevara, Naveenchandra; Sornberger, Ty A; Zost, Seth J; Parks, Robert; Flaherty, Shelby; Janke, Alexis K; Howard, Bethany N; Suresh, Yukthi P; Ruprecht, Ruth M; Crowe, James E Jr; Carnahan, Robert H; Bailey, Justin R; Kanekiyo, Masaru; Lingwood, Daniel; Haynes, Barton F; Moore, Penny L; Bonami, Rachel H; Tomaras, Georgia D; Archarya, Priyamvada; Montefiori, David C; Kalams, Spyros A; Lu, Shan; Georgiev, Ivelin S

Evaluating the antibody response elicited by diverse HIV envelope immunogens in the African green monkey (Vervet) model

在非洲绿猴(Vervet)模型中评估不同HIV包膜免疫原诱导的抗体反应

Moyo-Gwete, Thandeka; Ayres, Frances; Mzindle, Nonkululeko B; Makhado, Zanele; Manamela, Nelia P; Richardson, Simone I; Kitchin, Dale; van Graan, Strauss; van Heerden, Joritha; Parbhoo, Nishal; Chege, Gerald K; Moore, Penny L

Development of LIBRA-seq for the guinea pig model system as a tool for the evaluation of antibody responses to multivalent HIV-1 vaccines

开发用于豚鼠模型系统的LIBRA-seq作为评估多价HIV-1疫苗抗体反应的工具

Vukovich, Matthew J; Raju, Nagarajan; Kgagudi, Prudence; Manamela, Nelia P; Abu-Shmais, Alexandra A; Gripenstraw, Kathryn R; Wasdin, Perry T; Shen, Xiaoying; Dwyer, Bridget; Akoad, Jumana; Lynch, Rebecca M; Montefiori, David C; Richardson, Simone I; Moore, Penny L; Georgiev, Ivelin S

SARS-CoV-2 BA.4/5 infection triggers more cross-reactive FcγRIIIa signaling and neutralization than BA.1, in the context of hybrid immunity

在混合免疫的背景下,SARS-CoV-2 BA.4/5 感染比 BA.1 感染会引发更强的交叉反应性 FcγRIIIa 信号传导和中和作用。

Richardson, Simone I; Mzindle, Nonkululeko; Motlou, Thopisang; Manamela, Nelia P; van der Mescht, Mieke A; Lambson, Bronwen E; Everatt, Josie; Amoako, Daniel Gyamfi; Balla, Sashkia; von Gottberg, Anne; Wolter, Nicole; de Beer, Zelda; de Villiers, Talita Roma; Bodenstein, Annie; van den Berg, Gretha; Abdullah, Fareed; Rossouw, Theresa M; Boswell, Michael T; Ueckermann, Veronica; Bhiman, Jinal N; Moore, Penny L

Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants

在已接种Ad26.COV2.S疫苗的受试者中,加强免疫接种和分次接种Ad26.COV2.S或BNT162b2的安全性和免疫原性

Riou, Catherine; Bhiman, Jinal N; Ganga, Yashica; Sawry, Shobna; Ayres, Frances; Baguma, Richard; Balla, Sashkia R; Benede, Ntombi; Bernstein, Mallory; Besethi, Asiphe S; Cele, Sandile; Crowther, Carol; Dhar, Mrinmayee; Geyer, Sohair; Gill, Katherine; Grifoni, Alba; Hermanus, Tandile; Kaldine, Haajira; Keeton, Roanne S; Kgagudi, Prudence; Khan, Khadija; Lazarus, Erica; Le Roux, Jean; Lustig, Gila; Madzivhandila, Mashudu; Magugu, Siyabulela F J; Makhado, Zanele; Manamela, Nelia P; Mkhize, Qiniso; Mosala, Paballo; Motlou, Thopisang P; Mutavhatsindi, Hygon; Mzindle, Nonkululeko B; Nana, Anusha; Nesamari, Rofhiwa; Ngomti, Amkele; Nkayi, Anathi A; Nkosi, Thandeka P; Omondi, Millicent A; Panchia, Ravindre; Patel, Faeezah; Sette, Alessandro; Singh, Upasna; van Graan, Strauss; Venter, Elizabeth M; Walters, Avril; Moyo-Gwete, Thandeka; Richardson, Simone I; Garrett, Nigel; Rees, Helen; Bekker, Linda-Gail; Gray, Glenda; Burgers, Wendy A; Sigal, Alex; Moore, Penny L; Fairlie, Lee

Safety, effectiveness and immunogenicity of heterologous mRNA-1273 boost after prime with Ad26.COV2.S among healthcare workers in South Africa: The single-arm, open-label, phase 3 SHERPA study

在南非医护人员中,使用Ad26.COV2.S初次免疫后,异源mRNA-1273加强免疫的安全性、有效性和免疫原性:单臂、开放标签、3期SHERPA研究

Garrett, Nigel; Reddy, Tarylee; Yende-Zuma, Nonhlanhla; Takalani, Azwidhwi; Woeber, Kubashni; Bodenstein, Annie; Jonas, Phumeza; Engelbrecht, Imke; Jassat, Waasila; Moultrie, Harry; Bradshaw, Debbie; Seocharan, Ishen; Odhiambo, Jackline; Khuto, Kentse; Richardson, Simone I; Omondi, Millicent A; Nesamari, Rofhiwa; Keeton, Roanne S; Riou, Catherine; Moyo-Gwete, Thandeka; Innes, Craig; Zwane, Zwelethu; Mngadi, Kathy; Brumskine, William; Naicker, Nivashnee; Potloane, Disebo; Badal-Faesen, Sharlaa; Innes, Steve; Barnabas, Shaun; Lombaard, Johan; Gill, Katherine; Nchabeleng, Maphoshane; Snyman, Elizma; Petrick, Friedrich; Spooner, Elizabeth; Naidoo, Logashvari; Kalonji, Dishiki; Naicker, Vimla; Singh, Nishanta; Maboa, Rebone; Mda, Pamela; Malan, Daniel; Nana, Anusha; Malahleha, Mookho; Kotze, Philip; Allagappen, Jon J; Diacon, Andreas H; Kruger, Gertruida M; Patel, Faeezah; Moore, Penny L; Burgers, Wendy A; Anteyi, Kate; Leav, Brett; Bekker, Linda-Gail; Gray, Glenda E; Goga, Ameena

Hemagglutinin Stalk-Specific Fc-Mediated Functions Are Associated With Protection Against Influenza Illness After Seasonal Influenza Vaccination

血凝素茎特异性Fc介导的功能与季节性流感疫苗接种后对流感的保护作用相关

Motsoeneng, Boitumelo M; Dhar, Nisha; Nunes, Marta C; Krammer, Florian; Madhi, Shabir A; Moore, Penny L; Richardson, Simone I

Durability of ChAdOx1 nCoV-19 (AZD1222) vaccine and hybrid humoral immunity against variants including omicron BA.1 and BA.4 6 months after vaccination (COV005): a post-hoc analysis of a randomised, phase 1b-2a trial

ChAdOx1 nCoV-19 (AZD1222) 疫苗接种后 6 个月针对包括 omicron BA.1 和 BA.4 在内的变异株的持久性及混合体液免疫(COV005):一项随机 1b-2a 期试验的事后分析

Madhi, Shabir A; Kwatra, Gaurav; Richardson, Simone I; Koen, Anthonet L; Baillie, Vicky; Cutland, Clare L; Fairlie, Lee; Padayachee, Sherman D; Dheda, Keertan; Barnabas, Shaun L; Bhorat, Qasim Ebrahim; Briner, Carmen; Ahmed, Khatija; Aley, Parvinder K; Bhikha, Sutika; Bhorat, A E; Esmail, Aliasgar; Horne, Elizea; Kaldine, Haajira; Mukendi, Christian K; Madzorera, Vimbai Sharon; Manamela, Nelia P; Masilela, Mduduzi; Hermanus, S Tandile; Motlou, Thopisang; Mzindle, Nonkululeko; Oelofse, Suzette; Patel, Faeezah; Rhead, Sarah; Rossouw, Lindie; Taoushanis, Carol; van Eck, Samuel; Lambe, Teresa; Gilbert, Sarah C; Pollard, Andrew J; Moore, Penny L; Izu, Alane

Homologous Ad26.COV2.S vaccination results in reduced boosting of humoral responses in hybrid immunity, but elicits antibodies of similar magnitude regardless of prior infection

同源Ad26.COV2.S疫苗接种会导致混合免疫中体液反应的增强作用减弱,但无论先前是否感染,都能诱导产生相似水平的抗体。

Moyo-Gwete, Thandeka; Richardson, Simone I; Keeton, Roanne; Hermanus, Tandile; Spencer, Holly; Manamela, Nelia P; Ayres, Frances; Makhado, Zanele; Motlou, Thopisang; Tincho, Marius B; Benede, Ntombi; Ngomti, Amkele; Baguma, Richard; Chauke, Masego V; Mennen, Mathilda; Adriaanse, Marguerite; Skelem, Sango; Goga, Ameena; Garrett, Nigel; Bekker, Linda-Gail; Gray, Glenda; Ntusi, Ntobeko A B; Riou, Catherine; Burgers, Wendy A; Moore, Penny L