日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Highly cross-reactive and competent effectors dominate the CD8+ T cell response in Trypanosoma cruzi infection

在克氏锥虫感染中,具有高度交叉反应性和强大效应能力的细胞主导了CD8+ T细胞反应。

Molly E Bunkofske ,Pradyot Dash ,Walid Awad ,Paul G Thomas ,Rick L Tarleton

Frequency Variation and Dose Modification of Benznidazole Administration for the Treatment of Trypanosoma cruzi Infection in Mice, Dogs, and Nonhuman Primates

苯并硝唑给药频率变化和剂量调整用于治疗小鼠、狗和非人类灵长类动物克氏锥虫感染

Juan M Bustamante, Brooke E White, Gregory K Wilkerson, Carolyn L Hodo, Lisa D Auckland, Wei Wang, Stephanie McCain, Sarah A Hamer, Ashley B Saunders, Rick L Tarleton

cGAS-STING Pathway Activation during Trypanosoma cruzi Infection Leads to Tissue-Dependent Parasite Control

克氏锥虫感染期间 cGAS-STING 通路激活可实现组织依赖性寄生虫控制

Natasha Perumal, Brooke White, Fernando Sanchez-Valdez, Rick L Tarleton

Frequency variation and dose modification of benznidazole administration for the treatment of Trypanosoma cruzi infection in mice, dogs and non-human primates

苯并硝唑给药频率变化和剂量调整用于治疗小鼠、狗和非人类灵长类动物克氏锥虫感染

Juan M Bustamante, Brooke E White, Gregory K Wilkerson, Carolyn L Hodo, Lisa D Auckland, Wei Wang, Stephanie McCain, Sarah A Hamer, Ashley B Saunders, Rick L Tarleton

Discovery of an orally active benzoxaborole prodrug effective in the treatment of Chagas disease in non-human primates

发现一种口服活性苯并氧硼烷前药,可有效治疗非人类灵长类动物的恰加斯病

Angel M Padilla #, Wei Wang #, Tsutomu Akama, David S Carter, Eric Easom, Yvonne Freund, Jason S Halladay, Yang Liu, Sarah A Hamer, Carolyn L Hodo, Gregory K Wilkerson, Dylan Orr, Brooke White, Arlene George, Huifeng Shen, Yiru Jin, Michael Zhuo Wang, Susanna Tse, Robert T Jacobs #, Rick L Tarleton 

Prophylactic low-dose, bi-weekly benznidazole treatment fails to prevent Trypanosoma cruzi infection in dogs under intense transmission pressure

每两周进行一次低剂量苯并硝唑预防性治疗无法预防在巨大传播压力下的犬只感染克氏锥虫

Juan M Bustamante, Angel M Padilla, Brooke White, Lisa D Auckland, Rachel E Busselman, Stephanie Collins, Elizabeth L Malcolm, Briana F Wilson, Ashley B Saunders, Sarah A Hamer, Rick L Tarleton

A flexible, pan-species, multi-antigen platform for the detection and monitoring of SARS-CoV-2-specific antibody responses

一种灵活的泛物种多抗原平台,用于检测和监测 SARS-CoV-2 特异性抗体反应

Huifeng Shen, David Forgacs, Digantkumar Chapla, Kelley W Moremen, Lance Wells, Sarah A Hamer, Stephen M Tompkins, Ted M Ross, Nadine Rouphael, Srilatha Edupuganti, Matthew H Collins, Rick L Tarleton

Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure

自发休眠可在长期药物暴露期间保护克氏锥虫

Fernando J Sánchez-Valdéz #, Angel Padilla #, Wei Wang, Dylan Orr, Rick L Tarleton

Rapid, Selection-Free, High-Efficiency Genome Editing in Protozoan Parasites Using CRISPR-Cas9 Ribonucleoproteins

使用 CRISPR-Cas9 核糖核蛋白对原生动物寄生虫进行快速、无选择、高效的基因组编辑

Lia Carolina Soares Medeiros, Lilith South, Duo Peng, Juan M Bustamante, Wei Wang, Molly Bunkofske, Natasha Perumal, Fernando Sanchez-Valdez, Rick L Tarleton

Long-Term Immunity to Trypanosoma cruzi in the Absence of Immunodominant trans-Sialidase-Specific CD8+ T Cells

在没有免疫显性反式唾液酸酶特异性 CD8+ T 细胞的情况下对克氏锥虫的长期免疫力

Charles S Rosenberg, Weibo Zhang, Juan M Bustamante, Rick L Tarleton