日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TMIC-98. Single-cell profiling of peripheral and local immune compartments reveal unique genotype- independent prognostic immune signatures across IDH-stratified glioma

TMIC-98。外周和局部免疫区室的单细胞分析揭示了IDH分层胶质瘤中独特的、与基因型无关的预后免疫特征。

Volfson-Sedletsky, Victoria; DeBerg, Hannah A; Fahning, Mitch L; Rifkin, Ian R; Bujor, Andreea M; Campbell, Daniel J; Morawski, Peter A; Belkina, Anna C; Dooms, Hans; Yu, Kenny Kwok Hei; Abou-Mrad, Zaki; Törkenczy, Kristof; Schulze, Isabell; Gantchev, Jennifer; Baquer, Gerard; Hopland, Kelsey; Bander, Evan D; Tosi, Umberto; Brennan, Cameron; Moss, Nelson S; Hamard, Pierre-Jacques; Koche, Richard; Lareau, Caleb; Agar, Nathalie Y R; Merghoub, Taha; Tabar, Viviane; Garfinkle, Elizabeth; Perales-Linares, Renzo; Gimple, Ryan; Yan, Jian; Navarro, Jaye; Paxton, Sophia; Livingstone, Alexandra; Roberts, Kaleigh; Cooch, Neil; Perales-Puchalt, Alfredo; Rochestie, Sarah; Peters, Joann; Campian, Jian; Junker, Beth; Chheda, Milan; Chicoine, Michael; Kim, Albert; Willie, Jon; Zipfel, Gregory; Dowling, Joshua; Gillanders, William; Miller, Katherine; Mardis, Elaine; Sardesai, Niranjan; Dunn, Gavin; Johanns, Tanner; Sussman, Jonathan H; Cillo, Anthony R; Cardello, Carly; Patterson, Jonathan; Akca, Ebrar; Angione, Angelo; Krueger, Katharine; Xu, Emily; Xu, Jessica; Tarbay, Antonio C; Li, Alex; Budihal, Bhargavi R; Zhang, Xiaoran; Elghawy, Omar; Rajappa, Prajwal; Tan, Kai; Vignali, Dario A A; Bruno, Tullia C; Amankulor, Nduka M

Follicular Dendritic Cell Activation by TLR Ligands Promotes Autoreactive B Cell Responses

TLR配体激活滤泡树突状细胞促进自身反应性B细胞应答

Das, Abhishek; Heesters, Balthasar A; Bialas, Allison; O'Flynn, Joseph; Rifkin, Ian R; Ochando, Jordi; Mittereder, Nanette; Carlesso, Gianluca; Herbst, Ronald; Carroll, Michael C

Promotion of Inflammatory Arthritis by Interferon Regulatory Factor 5 in a Mouse Model

干扰素调节因子 5 在小鼠模型中促进炎症性关节炎

Duffau, Pierre; Menn-Josephy, Hanni; Cuda, Carla M; Dominguez, Salina; Aprahamian, Tamar R; Watkins, Amanda A; Yasuda, Kei; Monach, Paul; Lafyatis, Robert; Rice, Lisa M; Kenneth Haines, G 3rd; Gravallese, Ellen M; Baum, Rebecca; Richez, Christophe; Perlman, Harris; Bonegio, Ramon G; Rifkin, Ian R

Inhibition of type 4 cyclic nucleotide phosphodiesterase blocks intracellular TLR signaling in chronic lymphocytic leukemia and normal hematopoietic cells

抑制4型环核苷酸磷酸二酯酶可阻断慢性淋巴细胞白血病和正常造血细胞中的细胞内TLR信号传导。

Tan, Ying; Watkins, Amanda A; Freeman, Benjamin B; Meyers, John A; Rifkin, Ian R; Lerner, Adam

IRF5 deficiency ameliorates lupus but promotes atherosclerosis and metabolic dysfunction in a mouse model of lupus-associated atherosclerosis

IRF5 缺陷可改善狼疮症状,但在狼疮相关动脉粥样硬化的小鼠模型中会促进动脉粥样硬化和代谢功能障碍。

Watkins, Amanda A; Yasuda, Kei; Wilson, Gabriella E; Aprahamian, Tamar; Xie, Yao; Maganto-Garcia, Elena; Shukla, Prachi; Oberlander, Lillian; Laskow, Bari; Menn-Josephy, Hanni; Wu, Yuanyuan; Duffau, Pierre; Fried, Susan K; Lichtman, Andrew H; Bonegio, Ramon G; Rifkin, Ian R

The immunomodulatory parasitic worm product ES-62 reduces lupus-associated accelerated atherosclerosis in a mouse model

免疫调节寄生虫产物ES-62可减轻小鼠模型中狼疮相关的加速动脉粥样硬化

Aprahamian, Tamar R; Zhong, Xuemei; Amir, Shahzada; Binder, Christoph J; Chiang, Lo-Ku; Al-Riyami, Lamyaa; Gharakhanian, Raffi; Harnett, Margaret M; Harnett, William; Rifkin, Ian R

CpGB DNA activates dermal macrophages and specifically recruits inflammatory monocytes into the skin.

CpGB DNA 可激活真皮巨噬细胞,并特异性地将炎症单核细胞募集到皮肤中

Mathes Allison L, Rice Lisa, Affandi Alsya J, DiMarzio Michael, Rifkin Ian R, Stifano Giuseppina, Christmann Romy B, Lafyatis Robert

Peroxisome proliferator-activated receptor gamma agonists in the prevention and treatment of murine systemic lupus erythematosus

过氧化物酶体增殖物激活受体γ激动剂在预防和治疗小鼠系统性红斑狼疮中的应用

Aprahamian, Tamar R; Bonegio, Ramon G; Weitzner, Zachary; Gharakhanian, Raffi; Rifkin, Ian R

The effect of mycophenolate mofetil on disease development in the gld.apoE (-/-) mouse model of accelerated atherosclerosis and systemic lupus erythematosus

吗替麦考酚酯对 gld.apoE (-/-) 小鼠加速动脉粥样硬化和系统性红斑狼疮模型疾病发展的影响

Richez, Christophe; Richards, Rocco J; Duffau, Pierre; Weitzner, Zachary; Andry, Christopher D; Rifkin, Ian R; Aprahamian, Tamar

IFN regulatory factor 5 is required for disease development in the FcgammaRIIB-/-Yaa and FcgammaRIIB-/- mouse models of systemic lupus erythematosus

IFN调节因子5是FcγRIIB-/-Yaa和FcγRIIB-/-系统性红斑狼疮小鼠模型中疾病发展所必需的

Richez, Christophe; Yasuda, Kei; Bonegio, Ramon G; Watkins, Amanda A; Aprahamian, Tamar; Busto, Patricia; Richards, Rocco J; Liu, Chih Long; Cheung, Regina; Utz, Paul J; Marshak-Rothstein, Ann; Rifkin, Ian R