日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Costimulatory blockade depletes T peripheral helper, late-activated naïve, and DN2 B cells in rheumatoid arthritis

共刺激阻断会耗竭类风湿性关节炎中的外周辅助性T细胞、晚期激活的幼稚B细胞和DN2 B细胞

Shwetar, Jasmine J; Amarnani, Abhimanyu; Rigby, William; Skopelia-Gardner, Sladjana; Ruggles, Kelly V; Silverman, Gregg J

Upadacitinib as monotherapy in patients with rheumatoid arthritis and prior inadequate response to methotrexate: results at 260 weeks from the SELECT-MONOTHERAPY randomised study

乌帕替尼单药治疗既往对甲氨蝶呤反应不足的类风湿性关节炎患者:SELECT-MONOTHERAPY随机研究260周结果

Smolen, Josef S; Emery, Paul; Rigby, William; Tanaka, Yoshiya; Vargas, Juan Ignacio; Jain, Manish; Kato, Koji; Carter, Kyle M; Khan, Nasser; Phillips, Charles; Meerwein, Sebastian; Cohen, Stanley B

Benefit-Risk Analysis of Upadacitinib Compared with Adalimumab in the Treatment of Patients with Moderate-to-Severe Rheumatoid Arthritis

乌帕替尼与阿达木单抗治疗中重度类风湿性关节炎患者的获益风险分析

Conaghan, Philip; Cohen, Stanley; Burmester, Gerd; Mysler, Eduardo; Nash, Peter; Tanaka, Yoshiya; Rigby, William; Patel, Jayeshkumar; Shaw, Tim; Betts, Keith A; Patel, Pankaj; Liu, Jianzhong; Sun, Rochelle; Fleischmann, Roy

Journal Club: Efficacy of Tocilizumab in Early Systemic Sclerosis-Related Interstitial Lung Disease

期刊俱乐部:托珠单抗治疗早期系统性硬化症相关间质性肺病的疗效

Tiwari, Vivekanand; Rigby, William F C

Filgotinib in combination with methotrexate or as monotherapy versus methotrexate monotherapy in patients with active rheumatoid arthritis and limited or no prior exposure to methotrexate: the phase 3, randomised controlled FINCH 3 trial

在既往未接受过甲氨蝶呤治疗或接受过甲氨蝶呤治疗的活动性类风湿关节炎患者中,菲戈替尼联合甲氨蝶呤或单药治疗与甲氨蝶呤单药治疗的疗效比较:FINCH 3 期随机对照试验

Westhovens, René; Rigby, William F C; van der Heijde, Désirée; Ching, Daniel W T; Stohl, William; Kay, Jonathan; Chopra, Arvind; Bartok, Beatrix; Matzkies, Franziska; Yin, Zhaoyu; Guo, Ying; Tasset, Chantal; Sundy, John S; Jahreis, Angelika; Mozaffarian, Neelufar; Messina, Osvaldo Daniel; Landewé, Robert Bm; Atsumi, Tatsuya; Burmester, Gerd R

Bactericidal/Permeability-Increasing Protein Preeminently Mediates Clearance of Pseudomonas aeruginosa In Vivo via CD18-Dependent Phagocytosis.

杀菌/通透性增强蛋白主要通过 CD18 依赖性吞噬作用介导体内铜绿假单胞菌的清除

Theprungsirikul Jomkuan, Skopelja-Gardner Sladjana, Burns Ashley S, Wierzbicki Rachel M, Rigby William F C

The extracellular loop of the membrane permease VraG interacts with GraS to sense cationic antimicrobial peptides in Staphylococcus aureus.

膜渗透酶 VraG 的胞外环与 GraS 相互作用,从而感知金黄色葡萄球菌中的阳离子抗菌肽

Cho Junho, Costa Stephen K, Wierzbicki Rachel M, Rigby William F C, Cheung Ambrose L

HLA-DRB1 risk alleles for RA are associated with differential clinical responsiveness to abatacept and adalimumab: data from a head-to-head, randomized, single-blind study in autoantibody-positive early RA

HLA-DRB1 类风湿关节炎风险等位基因与阿巴西普和阿达木单抗的临床反应差异相关:一项针对自身抗体阳性早期类风湿关节炎患者的头对头、随机、单盲研究的数据

Rigby, William; Buckner, Jane H; Louis Bridges, S Jr; Nys, Marleen; Gao, Sheng; Polinsky, Martin; Ray, Neelanjana; Bykerk, Vivian

Upadacitinib in Rheumatoid Arthritis: A Benefit-Risk Assessment Across a Phase III Program

Upadacitinib治疗类风湿性关节炎:一项III期临床试验的获益-风险评估

Conaghan, Philip G; Mysler, Eduardo; Tanaka, Yoshiya; Da Silva-Tillmann, Barbara; Shaw, Tim; Liu, John; Ferguson, Ryan; Enejosa, Jeffrey V; Cohen, Stanley; Nash, Peter; Rigby, William; Burmester, Gerd

Killing three birds with one BPI: Bactericidal, opsonic, and anti-inflammatory functions

一举三得:BPI 兼具杀菌、调理和抗炎功能

Theprungsirikul, Jomkuan; Skopelja-Gardner, Sladjana; Rigby, William F C