日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Onboard, tethered IL-12 boosts potency of the Tmod NOT gate and preserves selectivity.

机载连接的 IL-12 可增强 Tmod NOT 门的效力并保持选择性

Zhang Jingli A, Imboden Sara, Lee Dongwoo, Zampieri Alexandre, Shafaattalab Sanam, Liang Jushen, Bruno Richele, Torres Jon, Partin Alexander, Daris Mark E, Riley Timothy P, Kamb Alexander

Multi-targeted, NOT gated CAR-T cells as a strategy to protect normal lineages for blood cancer therapy.

多靶点、非门控 CAR-T 细胞作为保护正常细胞谱系进行血液癌症治疗的策略

DiAndreth Breanna, Nesterenko Pavlo A, Winters Aaron G, Flynn Aaron D, Jette Claudia A, Suryawanshi Vasantika, Shafaattalab Sanam, Martire Sara, Daris Mark, Moore Elizabeth, Elshimali Ryan, Gill Tanveer, Riley Timothy P, Miller Sara, Netirojjanakul Chawita, Hamburger Agnes E, Kamb Alexander

EP08.01 THE IMMUNE LANDSCAPE OF BRAIN TUMORS: IMPLICATIONS FOR NEUROIMMUNOLOGY AND NEURO-ONCOLOGY THERAPIES

EP08.01 脑肿瘤的免疫图谱:对神经免疫学和神经肿瘤学治疗的启示

Paulsen, Erna-Elise; Andersen, Sigve; Rakaee, Mehrdad; Pedersen, Mona Irene; Lombardi, Ana Paola; Pøhl, Mette; Kilvaer, Thomas; Busund, Lill-Tove; Pezzella, Francesco; Donnem, Tom; Hough, Sara D; Chen, Zhihua; Long, Xidai; Miao, Yifeng; Zhou, Xuan; Rockne, Russell; Riley, Timothy P; Mendoza, Juan; Garcia, K C; Baker, Brian M; Thaysen-Andersen, Morten; Suckau, Detlev; Karen, Jonscher; Kolarich, Daniel; Orlando, Ron; Mccomb, Mark; Zaia, Joseph; Leymarie, Nancy; Alnahdi, M

Toward generalizable prediction of antibody thermostability using machine learning on sequence and structure features

利用机器学习技术,基于序列和结构特征,实现对抗体热稳定性的通用预测。

Harmalkar, Ameya; Rao, Roshan; Richard Xie, Yuxuan; Honer, Jonas; Deisting, Wibke; Anlahr, Jonas; Hoenig, Anja; Czwikla, Julia; Sienz-Widmann, Eva; Rau, Doris; Rice, Austin J; Riley, Timothy P; Li, Danqing; Catterall, Hannah B; Tinberg, Christine E; Gray, Jeffrey J; Wei, Kathy Y

The intersection of affinity and specificity in the development and optimization of T cell receptor based therapeutics

T细胞受体疗法开发和优化中亲和力和特异性的交汇点

Riley, Timothy P; Baker, Brian M

Modeling Sequence-Dependent Peptide Fluctuations in Immunologic Recognition

免疫识别中序列依赖性肽波动的建模

Ayres, Cory M; Riley, Timothy P; Corcelli, Steven A; Baker, Brian M

Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes

TCR特异性的新兴概念:合理化和(或许)预测结果

Singh, Nishant K; Riley, Timothy P; Baker, Sarah Catherine B; Borrman, Tyler; Weng, Zhiping; Baker, Brian M

Hepatitis C virus-cross-reactive TCR gene-modified T cells: a model for immunotherapy against diseases with genomic instability

丙型肝炎病毒交叉反应性TCR基因修饰的T细胞:一种针对基因组不稳定性疾病的免疫疗法模型

Spear, Timothy T; Riley, Timothy P; Lyons, Gretchen E; Callender, Glenda G; Roszkowski, Jeffrey J; Wang, Yuan; Simms, Patricia E; Scurti, Gina M; Foley, Kendra C; Murray, David C; Hellman, Lance M; McMahan, Rachel H; Iwashima, Makio; Garrett-Mayer, Elizabeth; Rosen, Hugo R; Baker, Brian M; Nishimura, Michael I

Differential scanning fluorimetry based assessments of the thermal and kinetic stability of peptide-MHC complexes

基于差示扫描荧光法的肽-MHC复合物热稳定性和动力学稳定性评估

Hellman, Lance M; Yin, Liusong; Wang, Yuan; Blevins, Sydney J; Riley, Timothy P; Belden, Orrin S; Spear, Timothy T; Nishimura, Michael I; Stern, Lawrence J; Baker, Brian M