日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

De novo design of peptide binders to conformationally diverse targets with contrastive language modeling

利用对比语言模型对构象不同的靶标进行肽结合剂的从头设计

Suhaas Bhat, Kalyan Palepu, Lauren Hong, Joey Mao, Tianzheng Ye, Rema Iyer, Lin Zhao, Tianlai Chen, Sophia Vincoff, Rio Watson, Tian Z Wang, Divya Srijay, Venkata Srikar Kavirayuni, Kseniia Kholina, Shrey Goel, Pranay Vure, Aniruddha J Deshpande, Scott H Soderling, Matthew P DeLisa, Pranam Chatterje

Programmable Protein Stabilization with Language Model-Derived Peptide Guides

利用语言模型衍生的肽指南进行可编程蛋白质稳定

Lauren Hong, Tianzheng Ye, Tian Zi Wang, Divya Srijay, Lin Zhao, Rio Watson, Sophia Vincoff, Tianlai Chen, Kseniia Kholina, Shrey Goel, Matthew P DeLisa, Pranam Chatterjee

De Novo Design of Peptide Binders to Conformationally Diverse Targets with Contrastive Language Modeling

使用对比语言模型对构象多样的靶标进行肽结合剂的从头设计

Suhaas Bhat, Kalyan Palepu, Lauren Hong, Joey Mao, Tianzheng Ye, Rema Iyer, Lin Zhao, Tianlai Chen, Sophia Vincoff, Rio Watson, Tian Wang, Divya Srijay, Venkata Srikar Kavirayuni, Kseniia Kholina, Shrey Goel, Pranay Vure, Aniruddha J Desphande, Scott H Soderling, Matthew P DeLisa, Pranam Chatterjee