日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of supramolecular anticoagulants with on-demand reversibility

按需可逆性超分子抗凝剂的开发

Millicent Dockerill, Daniel J Ford, Simona Angerani, Imala Alwis, Luke J Dowman, Jorge Ripoll-Rozada, Rhyll E Smythe, Joanna S T Liu, Pedro José Barbosa Pereira, Shaun P Jackson, Richard J Payne, Nicolas Winssinger

Engineering ultrapotent trivalent anticoagulants through hybridisation of salivary peptides from multiple haematophagous organisms

通过杂交多种吸血生物的唾液肽来构建超强效三价抗凝血剂

Maxwell, Joshua W C; Ripoll-Rozada, Jorge; Mackay, Angus S; Alwis, Imala; Ford, Daniel J; Trought, Cameron B J; Santos, Joana A; Smythe, Rhyll E; Liu, Joanna S T; Zuccolotto, Zack; Schoenwaelder, Simone M; Jackson, Shaun P; Pereira, Pedro José Barbosa; Payne, Richard J

Protocol for an automated virtual screening pipeline including library generation and docking evaluation

自动化虚拟筛选流程方案,包括文库生成和对接评估

Barbosa Pereira, Pedro José; Ripoll-Rozada, Jorge; Macedo-Ribeiro, Sandra; Manso, José Antonio

Self-recycling and partially conservative replication of mycobacterial methylmannose polysaccharides

分枝杆菌甲基甘露糖多糖的自我循环和部分保守复制

Maranha, Ana; Costa, Mafalda; Ripoll-Rozada, Jorge; Manso, José A; Miranda, Vanessa; Mendes, Vera M; Manadas, Bruno; Macedo-Ribeiro, Sandra; Ventura, M Rita; Pereira, Pedro José Barbosa; Empadinhas, Nuno

Rapid assembly and profiling of an anticoagulant sulfoprotein library

快速构建和分析抗凝血磺蛋白库

Watson, Emma E; Ripoll-Rozada, Jorge; Lee, Ashley C; Wu, Mike C L; Franck, Charlotte; Pasch, Tim; Premdjee, Bhavesh; Sayers, Jessica; Pinto, Maria F; Martins, Pedro M; Jackson, Shaun P; Pereira, Pedro José Barbosa; Payne, Richard J

Mosquito-Derived Anophelin Sulfoproteins Are Potent Antithrombotics

蚊源性按蚊素硫蛋白是强效抗血栓药物

Watson, Emma E; Liu, Xuyu; Thompson, Robert E; Ripoll-Rozada, Jorge; Wu, Mike; Alwis, Imala; Gori, Alessandro; Loh, Choy-Theng; Parker, Benjamin L; Otting, Gottfried; Jackson, Shaun; Pereira, Pedro José Barbosa; Payne, Richard J

In silico and crystallographic studies identify key structural features of biliverdin IXβ reductase inhibitors having nanomolar potency

通过计算机模拟和晶体学研究确定了具有纳摩尔效力的胆绿素 IXβ 还原酶抑制剂的关键结构特征

Natasha M Nesbitt, Xiliang Zheng, Zongdong Li, José A Manso, Wan-Yi Yen, Lisa E Malone, Jorge Ripoll-Rozada, Pedro José Barbosa Pereira, Timothy J Mantle, Jin Wang, Wadie F Bahou

Functional analyses yield detailed insight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from Anopheles gambiae.

功能分析详细揭示了冈比亚按蚊抗凝血唾液蛋白 cE5 抑制凝血酶的机制

Pirone Luciano, Ripoll-Rozada Jorge, Leone Marilisa, Ronca Raffaele, Lombardo Fabrizio, Fiorentino Gabriella, Andersen John F, Pereira Pedro José Barbosa, Arcà Bruno, Pedone Emilia

Type IV traffic ATPase TrwD as molecular target to inhibit bacterial conjugation

以IV型运输ATPase TrwD为分子靶点抑制细菌结合

Jorge Ripoll-Rozada, Yolanda García-Cazorla, María Getino, Cristina Machón, David Sanabria-Ríos, Fernando de la Cruz, Elena Cabezón, Ignacio Arechaga

Autoinhibitory regulation of TrwK, an essential VirB4 ATPase in type IV secretion systems

TrwK(IV型分泌系统中一种重要的VirB4 ATPase)的自身抑制调节

Peña, Alejandro; Ripoll-Rozada, Jorge; Zunzunegui, Sandra; Cabezón, Elena; de la Cruz, Fernando; Arechaga, Ignacio