Rishavy相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

GGCX mutants that impair hemostasis reveal the importance of processivity and full carboxylation to VKD protein function

GGCX突变体损害止血功能，揭示了VKD蛋白的加工性和完全羧化对其功能的重要性。

影响因子:23.1

doi:10.1182/blood.2021014275

Rishavy, Mark A; Hallgren, Kevin W; Wilson, Lee A; Hiznay, James M; Runge, Kurt W; Berkner, Kathleen L

发表日期：2022

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Exon 2 skipping eliminates γ-glutamyl carboxylase activity, indicating a partial splicing defect in a patient with vitamin K clotting factor deficiency

外显子2跳跃导致γ-谷氨酰羧化酶活性丧失，表明维生素K凝血因子缺乏症患者存在部分剪接缺陷。

期刊:Journal of Thrombosis and Haemostasis

doi:10.1111/jth.14456

Rishavy, Mark A; Hallgren, Kevin W; Zhang, Haitao; Runge, Kurt W; Berkner, Kathleen L

发表日期：2019

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Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase

华法林会改变维生素K代谢：VKORC1解偶联的一种令人惊讶的机制需要额外的还原酶

影响因子:23.1

doi:10.1182/blood-2017-09-804666

Rishavy, Mark A; Hallgren, Kevin W; Wilson, Lee; Singh, Savita; Runge, Kurt W; Berkner, Kathleen L

发表日期：2018

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VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo

VKOR 同源物 VKORC1L1 支持体内维生素 K 依赖性蛋白质羧化

期刊:JCI Insight

影响因子:6.3

doi:10.1172/jci.insight.96501

Julie Lacombe, Mark A Rishavy, Kathleen L Berkner, Mathieu Ferron

发表日期：2018

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The vitamin K oxidoreductase is a multimer that efficiently reduces vitamin K epoxide to hydroquinone to allow vitamin K-dependent protein carboxylation

维生素K氧化还原酶是一种多聚体，能高效地将维生素K环氧化物还原为氢醌，从而使维生素K依赖性蛋白质羧化得以进行。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M113.497297

Rishavy, Mark A; Hallgren, Kevin W; Wilson, Lee A; Usubalieva, Aisulu; Runge, Kurt W; Berkner, Kathleen L

发表日期：2013

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Vitamin K oxygenation, glutamate carboxylation, and processivity: defining the three critical facets of catalysis by the vitamin K-dependent carboxylase

维生素K氧化、谷氨酸羧化和持续性：定义维生素K依赖性羧化酶催化的三个关键方面

期刊:Advances in Nutrition

影响因子:9.2

doi:10.3945/an.111.001719

Rishavy, Mark A; Berkner, Kathleen L

发表日期：2012

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The vitamin K-dependent carboxylase generates γ-carboxylated glutamates by using CO2 to facilitate glutamate deprotonation in a concerted mechanism that drives catalysis

维生素K依赖性羧化酶利用CO2促进谷氨酸去质子化，从而生成γ-羧基化谷氨酸，这一协同机制驱动催化反应。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M111.249177

Rishavy, Mark A; Hallgren, Kevin W; Berkner, Kathleen L

发表日期：2011

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Mutations in the GGCX and ABCC6 genes in a family with pseudoxanthoma elasticum-like phenotypes

弹性纤维假黄瘤样表型家族中的 GGCX 和 ABCC6 基因突变

期刊:Journal of Investigative Dermatology

影响因子:5.7

doi:10.1038/jid.2008.271

Qiaoli Li, Dorothy K Grange, Nicole L Armstrong, Alison J Whelan, Maria Y Hurley, Mark A Rishavy, Kevin W Hallgren, Kathleen L Berkner, Leon J Schurgers, Qiujie Jiang, Jouni Uitto

发表日期：2009

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